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输血制品后可能由低钙血症诱发的心室颤动和尖端扭转型室速

Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration.

作者信息

Mosebach Christian M, Kluger Jeffrey

机构信息

Internal Medicine, University of Connecticut, Farmington, USA.

Cardiology, Hartford Hospital, Hartford, USA.

出版信息

Cureus. 2018 Dec 21;10(12):e3765. doi: 10.7759/cureus.3765.

DOI:10.7759/cureus.3765
PMID:30820384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6389027/
Abstract

A 35-year-old male underwent open-heart surgery and required multiple blood product transfusions. Citrate, a preservative in blood products, caused serum ionized calcium chelation leading to hypocalcemia, a prolonged corrected QT (QTc) interval, and separate episodes of ventricular fibrillation and torsades de pointes (TdP). This case highlights an uncommon complication of blood product transfusion-induced hypocalcemia with precipitant arrhythmia.

摘要

一名35岁男性接受了心脏直视手术，需要多次输注血液制品。血液制品中的防腐剂柠檬酸盐导致血清离子钙螯合，进而引发低钙血症、校正QT（QTc）间期延长，以及室颤和尖端扭转型室速（TdP）发作。本病例突出了血液制品输注所致低钙血症伴骤发性心律失常这一罕见并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/c8c4a0f3d80a/cureus-0010-00000003765-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/2f9676ac16c2/cureus-0010-00000003765-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/9475a2b2662e/cureus-0010-00000003765-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/aede026271f3/cureus-0010-00000003765-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/6468a21aee69/cureus-0010-00000003765-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/41b93ca7b020/cureus-0010-00000003765-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/c8c4a0f3d80a/cureus-0010-00000003765-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/2f9676ac16c2/cureus-0010-00000003765-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/9475a2b2662e/cureus-0010-00000003765-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/aede026271f3/cureus-0010-00000003765-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/6468a21aee69/cureus-0010-00000003765-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/41b93ca7b020/cureus-0010-00000003765-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f4c/6389027/c8c4a0f3d80a/cureus-0010-00000003765-i06.jpg

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