Ryave Jacob, Gunasekaran Tamilselvam, Sanders Robert A
Department of Small Animal Clinical Sciences, Michigan State University College of Veterinary Medicine, East Lansing, Michigan, USA.
Case Rep Vet Med. 2025 Jun 5;2025:9925419. doi: 10.1155/crve/9925419. eCollection 2025.
The objective of the study is to report a case of a dog that experienced sudden cardiac death due to ventricular fibrillation following a packed red cell transfusion. A 14-year-old, male castrated, American Staffordshire terrier dog was evaluated before a planned anesthetic event and was diagnosed with second-degree atrioventricular block. One week after the initial evaluation, the dog presented to an emergency facility for episodes of collapse and was diagnosed with hemoperitoneum secondary to splenic rupture. An emergency splenectomy was performed, but the dog developed regenerative anemia postsurgery and received a packed red blood cell transfusion. A Holter monitor was placed before the start of the transfusion due to concerns about previous rhythm abnormalities. Two hours after the blood transfusion, the dog experienced sudden cardiac arrest, and closed-chest cardiopulmonary resuscitation was unsuccessful. Analysis of the Holter recording revealed the onset of ventricular arrhythmias following transfusion that progressed to frequent polymorphic ventricular tachycardia and ventricular fibrillation. Additionally, QT interval prolongation was noted just before the onset of the ventricular arrhythmias on the Holter recording. To the authors' knowledge, this is the first report of a dog that suffered sudden cardiac death after a blood transfusion and discusses possible causes of ventricular arrhythmias.
本研究的目的是报告一例狗在输注浓缩红细胞后因室颤而发生心脏性猝死的病例。一只14岁、已绝育的雄性美国斯塔福郡梗犬在计划进行麻醉事件前接受评估，被诊断为二度房室传导阻滞。在初次评估一周后，这只狗因出现虚脱发作而被送往一家急诊机构，并被诊断为脾破裂继发的腹腔积血。进行了急诊脾切除术，但这只狗术后出现了再生性贫血，并接受了浓缩红细胞输注。由于担心之前的心律异常，在输血开始前放置了动态心电图监测仪。输血两小时后，这只狗发生了心脏骤停，胸外心肺复苏未成功。对动态心电图记录的分析显示，输血后出现室性心律失常，进展为频繁的多形性室性心动过速和室颤。此外，在动态心电图记录中，室性心律失常发作前注意到QT间期延长。据作者所知，这是第一例关于狗输血后发生心脏性猝死的报告，并讨论了室性心律失常的可能原因。
