Su Jingkai, Chen Ni, Yue Qiang, Wang Weina, Zhang Simin, Su Xiaorui
Department of Radiology, West China Hospital of Sichuan University, #37 GuoXue Xiang, Chengdu, 610041, Sichuan, China.
Childs Nerv Syst. 2019 May;35(5):871-874. doi: 10.1007/s00381-019-04102-6. Epub 2019 Feb 28.
Juvenile xanthogranuloma (JXG) is a benign, self-limiting histiocytic disorder of infancy and early childhood, usually presented as a single or multiple cutaneous lesions. The central nervous system is rarely affected by JXG. There were only a few reports of intracranial JXG cases which described its features on MR spectroscopy (MRS) and diffusion-weighted imaging (DWI), but its features on susceptibility-weighted imaging (SWI) and perfusion-weighted imaging (PWI) have not been reported yet. Here, we reported an intracranial JXG case which underwent multimodal MRI examinations including DWI, SWI, and PWI. The multimodal MRI provided a thorough insight into this disease and we found that intense enhancement and high perfusion may be important clues for the diagnosis.
幼年性黄色肉芽肿（JXG）是一种发生于婴儿期和儿童早期的良性、自限性组织细胞疾病，通常表现为单个或多个皮肤损害。中枢神经系统很少受JXG影响。仅有少数关于颅内JXG病例的报道描述了其磁共振波谱（MRS）和扩散加权成像（DWI）特征，但其磁敏感加权成像（SWI）和灌注加权成像（PWI）特征尚未见报道。在此，我们报告1例接受了包括DWI、SWI和PWI在内的多模态MRI检查的颅内JXG病例。多模态MRI对该疾病提供了全面的认识，我们发现强化明显和高灌注可能是诊断的重要线索。
