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[长期使用氟化钠治疗骨质疏松症后的氟中毒]

[Fluorosis following the long-term treatment of osteoporosis with sodium fluoride].

作者信息

Meseg S, Matzkowski H, Hasert V

出版信息

Z Gesamte Inn Med. 1986 Jan 1;41(1):22-4.

PMID:3082082
Abstract

The fluorosis in fluor-exposed workers has been known already since nearly 50 years. It is characterized by a massive regeneration of bones. The fluorosis is only rarely observed as a sequel of the sodium fluoride therapy of osteoporosis. Out of the number of our own patients a medicamentously induced fluorosis after a 12-year sodium fluoride therapy of a steroid osteoporosis is described. The pathological value of this iatrogenic fluorosis is relatively insignificant. Nevertheless, due to the picture of complaints resulting from this a sodium fluoride therapy should be controlled. In this case the lateral X-ray picture of the lumbar vertebral column serves as most important control parameters.

摘要

近50年来,人们已经知晓氟暴露工人的氟中毒情况。其特征是骨骼大量再生。氟中毒仅在极少数情况下作为骨质疏松症氟化钠治疗的后遗症出现。在我们自己的患者中,描述了一例因类固醇性骨质疏松症接受12年氟化钠治疗后发生药物性氟中毒的病例。这种医源性氟中毒的病理价值相对较小。然而,由于由此产生的一系列症状,氟化钠治疗应该受到监控。在这种情况下,腰椎的侧位X线片是最重要的监控参数。

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