Epileptology unit, neurology department, Nancy hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54035 Nancy, France; UMR 7039, CNRS, université de Lorraine, 54500 Nancy, France; Reference, Center for rare Epilepsies, Nancy hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54035 Nancy, France.
Epileptology unit, neurology department, Nancy hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54035 Nancy, France; Reference, Center for rare Epilepsies, Nancy hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54035 Nancy, France.
Rev Neurol (Paris). 2019 Mar;175(3):135-140. doi: 10.1016/j.neurol.2019.01.394. Epub 2019 Feb 28.
Cognitive consequences in epilepsy are often described in the following domains: verbal memory, language, executive functions, and attention. Attention is involved in all cognitive activities, and attention disorders (AD) are reported in patients with various neurological diseases. This paper proposes to define the concept of AD and its assessment, to consider their determinants in epilepsy and potential therapies (drug or not). ADs are reported in new onset epilepsy, generalized epilepsy of presumed genetic origin, and in focal epilepsy. In focal epilepsy, alertness and divided attention impairment are observed and seem to improve after successful curative surgery. Additional studies are needed to assess the prevalence and nature of AD related to status epilepticus. In the field of therapeutic strategies, anti-epileptic drugs show an impact on AD. Effects of antidepressive drug therapy are not reported, as well as psychotherapy. Cognitive rehabilitation on AD is a promising therapeutic intervention but specific studies are needed to assess its efficacy.
言语记忆、语言、执行功能和注意力。注意力涉及所有认知活动，并且在各种神经疾病患者中都有报道注意力障碍（AD）。本文旨在定义 AD 的概念及其评估方法，考虑其在癫痫中的决定因素以及潜在的治疗方法（药物或非药物）。AD 在新发癫痫、推测遗传起源的全面性癫痫和局灶性癫痫中均有报道。在局灶性癫痫中，观察到警觉性和注意力分散受损，并且在成功治愈性手术后似乎有所改善。需要进一步的研究来评估与癫痫持续状态相关的 AD 的患病率和性质。在治疗策略领域中，抗癫痫药物对 AD 有影响。尚未报道抗抑郁药物治疗的效果，也没有报道心理治疗。认知康复对 AD 是一种很有前途的治疗干预方法，但需要进行专门的研究来评估其疗效。
