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[实验性心肌坏死时肝脏和心肌中磺胺乙酰化及辅酶A浓度]

[Sulfanilimide acetylation and coenzyme A concentration in liver and heart muscle in experimental myocardial necrosis].

作者信息

Prashkyavichius A, Lukoshyavichus L, Yokubauskene V N

出版信息

Vopr Med Khim. 1978 Jul-Aug;24(4):475-9.

PMID:308276
Abstract

Sulfanilamide acetylation was inhibited and content of CoA was decreased in myocardium and liver tissue within the first day after occlusion of coronary arteries. Within 1-6 days after the occlusion the sulfanilamide acetylation and content of CoA were increased in the tissues studied; at the 12th day the reactions of acetylation were normalized in myocardium but remained at an increased level in the liver tissue. The content of CoA was similar to the values found in the normal state.

摘要

冠状动脉闭塞后第一天,心肌和肝组织中磺胺乙酰化受到抑制,辅酶A含量降低。闭塞后1 - 6天,所研究组织中的磺胺乙酰化和辅酶A含量增加;第12天,心肌中的乙酰化反应恢复正常,但肝组织中的仍处于升高水平。辅酶A含量与正常状态下的值相似。

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