• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[实验性心肌坏死时肝脏和心肌中磺胺乙酰化及辅酶A浓度]

[Sulfanilimide acetylation and coenzyme A concentration in liver and heart muscle in experimental myocardial necrosis].

作者信息

Prashkyavichius A, Lukoshyavichus L, Yokubauskene V N

出版信息

Vopr Med Khim. 1978 Jul-Aug;24(4):475-9.

PMID:308276
Abstract

Sulfanilamide acetylation was inhibited and content of CoA was decreased in myocardium and liver tissue within the first day after occlusion of coronary arteries. Within 1-6 days after the occlusion the sulfanilamide acetylation and content of CoA were increased in the tissues studied; at the 12th day the reactions of acetylation were normalized in myocardium but remained at an increased level in the liver tissue. The content of CoA was similar to the values found in the normal state.

摘要

冠状动脉闭塞后第一天,心肌和肝组织中磺胺乙酰化受到抑制,辅酶A含量降低。闭塞后1 - 6天,所研究组织中的磺胺乙酰化和辅酶A含量增加;第12天,心肌中的乙酰化反应恢复正常,但肝组织中的仍处于升高水平。辅酶A含量与正常状态下的值相似。

相似文献

1
[Sulfanilimide acetylation and coenzyme A concentration in liver and heart muscle in experimental myocardial necrosis].[实验性心肌坏死时肝脏和心肌中磺胺乙酰化及辅酶A浓度]
Vopr Med Khim. 1978 Jul-Aug;24(4):475-9.
2
Metabolism of sulfanilamide and related drugs in isolated rat and rabbit liver cells.
Drug Metab Dispos. 1980 Jul-Aug;8(4):205-7.
3
[Participation of cyclic nucleotides in the mechanism of regulation of the tissue pool of coenzyme A and the acetylizing capacity of rats].[环核苷酸在大鼠辅酶A组织库调节机制及乙酰化能力中的作用]
Vopr Med Khim. 1981 Jan-Feb;27(1):51-5.
4
[On the effect of carnitine on the acetylcholine content of the brain and cardiac muscle in vivo and on the acetylation of sulfanilamide in the liver].[关于肉碱对体内脑和心肌中乙酰胆碱含量以及肝脏中磺胺乙酰化作用的影响]
Acta Biol Med Ger. 1966;16(4):349-58.
5
[Relation between catecholamines metabolism and CoA content in rat tissues].
Ukr Biokhim Zh. 1977 Jul-Aug;49(4):31-4.
6
[Sulfanilamide absorption and acetylation in rats with experimental hyperlipidemia and cellular regulation of the process of acetylation].[实验性高脂血症大鼠中磺胺类药物的吸收与乙酰化及乙酰化过程的细胞调控]
Farmakol Toksikol. 1981 Jan-Feb;44(1):109-15.
7
Metabolism of sulfadimidine, sulfanilamide, p-aminobenzoic acid, and isoniazid in suspensions of parenchymal and nonparenchymal rat liver cells.磺胺二甲嘧啶、磺胺、对氨基苯甲酸和异烟肼在大鼠肝实质细胞和非实质细胞悬液中的代谢
Drug Metab Dispos. 1977 Nov-Dec;5(6):511-7.
8
Induction of sulfamethazine acetylation by hydrocortisone in the rabbit.氢化可的松对家兔磺胺二甲嘧啶乙酰化的诱导作用。
Drug Metab Dispos. 1988 Jan-Feb;16(1):110-5.
9
Acetylation of sulfanilamide and para-aminobenzoic acid in diabetic patients.糖尿病患者中磺胺类药物和对氨基苯甲酸的乙酰化作用
N Engl J Med. 1959 Aug 27;261:440-2. doi: 10.1056/NEJM195908272610907.
10
Hepatic CoA, S-acyl-CoA, biosynthetic precursors of the coenzyme and pantothenate-protein complexes in dietary pantothenic acid deficiency.膳食泛酸缺乏时肝脏辅酶A、S-酰基辅酶A、辅酶生物合成前体及泛酸-蛋白质复合物的情况。
Int J Vitam Nutr Res. 1987;57(1):71-7.