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本文引用的文献

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Current status of theranostics in prostate cancer.前列腺癌治疗学的现状。
Eur J Nucl Med Mol Imaging. 2018 Mar;45(3):471-495. doi: 10.1007/s00259-017-3882-2. Epub 2017 Dec 28.
2
Theranostic Concepts: More Than Just a Fashion Trend-Introduction and Overview.诊疗一体化概念:不止是一种时尚潮流——引言与概述
J Nucl Med. 2017 Sep;58(Suppl 2):1S-2S. doi: 10.2967/jnumed.117.199570.
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Nuclear Medicine in the Philippines: A Glance at the Past, a Gaze at the Present, and a Glimpse of the Future.菲律宾的核医学:回顾过去、审视现在、展望未来。
Asia Ocean J Nucl Med Biol. 2016 Summer;4(2):113-8. doi: 10.7508/aojnmb.2016.02.009.
4
The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours.国际原子能机构、欧洲核医学协会和核医学分子影像学会联合发布的神经内分泌肿瘤肽受体放射性核素治疗实践指南。
Eur J Nucl Med Mol Imaging. 2013 May;40(5):800-16. doi: 10.1007/s00259-012-2330-6.
5
THERANOSTICS: From Molecular Imaging Using Ga-68 Labeled Tracers and PET/CT to Personalized Radionuclide Therapy - The Bad Berka Experience.治疗学:从使用 Ga-68 标记示踪剂的分子成像到 PET/CT 以及个体化放射性核素治疗——Bad Berka 的经验。
Theranostics. 2012;2(5):437-47. doi: 10.7150/thno.3645. Epub 2012 May 7.
6
Generator-based PET radiopharmaceuticals for molecular imaging of tumours: on the way to THERANOSTICS.基于发生器的正电子发射断层扫描放射性药物用于肿瘤的分子成像:迈向治疗诊断一体化。
Dalton Trans. 2011 Jun 21;40(23):6104-11. doi: 10.1039/c0dt01504k. Epub 2011 Mar 29.
7
Biokinetics and imaging with the somatostatin receptor PET radioligand (68)Ga-DOTATOC: preliminary data.生长抑素受体PET放射性配体(68)Ga-DOTATOC的生物动力学与成像:初步数据
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Radioiodine and the treatment of hyperthyroidism: the early history.放射性碘与甲状腺功能亢进症的治疗:早期历史
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菲律宾治疗诊断学的兴起:克服挑战并带来希望。

The Emergence of Theranostics in the Philippines: Overcoming Challenges and Bringing Hope.

作者信息

Bautista Patricia A

机构信息

Department of Nuclear Medicine and PET Center, St. Luke's Medical Center, 279 E. Rodriguez Sr. Ave., 1112 Quezon City, Philippines.

出版信息

Nucl Med Mol Imaging. 2019 Feb;53(1):30-32. doi: 10.1007/s13139-018-0560-7. Epub 2018 Dec 18.

DOI:10.1007/s13139-018-0560-7
PMID:30828396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6377579/
Abstract

Medical managements are becoming personalized while diseases are being understood at the molecular level. Nuclear medicine is one of the fields actively contributing to this development. In particular, theranostics, a combinatorial term for therapy and diagnostics, enables accurate imaging and subsequent targeted radionuclide treatment. Due to its high impact in healthcare, many countries have begun to offer Ga-68 PET/CT scans and Lu-177 therapies. The Philippines has followed suit through the initiative of this author and able support of the administration and staff of St. Luke's Medical Center. The Ga-68 DOTATATE and PSMA PET/CT scans became officially available in January 2018 while the first peptide receptor radionuclide therapy for neuroendocrine tumor and first PSMA radioligand therapy for prostate cancer occurred in May and June 2018, respectively. Amidst past, present, and future challenges, theranostics has emerged in the Philippines, offering hope to cancer patients in the country.

摘要

随着疾病在分子水平上被逐步了解,医疗管理正变得更加个性化。核医学是积极推动这一发展的领域之一。特别是治疗诊断学,这个融合了治疗与诊断的术语,能够实现精准成像以及后续的靶向放射性核素治疗。鉴于其在医疗保健领域的重大影响,许多国家已开始提供镓 - 68正电子发射断层扫描/计算机断层扫描(Ga - 68 PET/CT)以及镥 - 177治疗。菲律宾在作者的倡议以及圣卢克医疗中心管理层和工作人员的有力支持下也采取了同样的举措。镓 - 68 奥曲肽和前列腺特异性膜抗原正电子发射断层扫描/计算机断层扫描(PSMA PET/CT)于2018年1月正式投入使用,而首例用于神经内分泌肿瘤的肽受体放射性核素治疗以及首例用于前列腺癌的PSMA放射性配体治疗分别于2018年5月和6月开展。尽管面临过去、现在和未来的诸多挑战,治疗诊断学已在菲律宾兴起,为该国的癌症患者带来了希望。