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联合营养溶液中脂肪乳剂的研究。

Studies on fat emulsions in combined nutrition solutions.

作者信息

Davis S S, Galloway M

出版信息

J Clin Hosp Pharm. 1986 Feb;11(1):33-45. doi: 10.1111/j.1365-2710.1986.tb00826.x.

Abstract

The effect of added Aminoplex, Glucoplex, nutrient additives and calcium chloride on the stability of a fat emulsion (Intralipid) has been examined. The conclusions are as follows: Aminoplex and Glucoplex do not cause a decrease in the physical stability of mixed systems that contain fat droplets stored at room temperature for at least 7 days. The mixed systems are stable even in the presence of high electrolyte loads (greater than 600 mmol litre-1 expressed in terms of monovalent cation). The amino acids in Aminoplex could be having a stabilizing effect on the emulsion system by the adsorption of components to the oil/water interface.

摘要

已研究了添加氨复盐、糖复盐、营养添加剂和氯化钙对脂肪乳剂(英脱利匹特)稳定性的影响。结论如下:氨复盐和糖复盐不会导致含有在室温下储存至少7天的脂肪滴的混合体系的物理稳定性下降。即使存在高电解质负荷(以单价阳离子计大于600 mmol/L),混合体系仍保持稳定。氨复盐中的氨基酸可能通过将组分吸附到油/水界面而对乳剂体系起到稳定作用。

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