Yale School of Medicine, Department of Internal Medicine, New Haven, Connecticut.
J Am Geriatr Soc. 2019 Jun;67(6):1248-1252. doi: 10.1111/jgs.15822. Epub 2019 Mar 4.
To evaluate the time course of "taking to bed" at the end of life and determine whether it differs according to age, sex, and condition leading to death.
Prospective longitudinal study.
Greater New Haven, Connecticut.
A total of 651 decedents from a cohort of 754 community-living persons, 70+ years of age.
During the last 2 years of life, the occurrence of bed rest and number of days in bed, two indicators of bed rest burden, were ascertained each month. Bed rest was defined as staying in bed for at least a half day due to an illness, injury, or other problem.
The occurrence of bed rest increased modestly from 12.4% at 24 months before death to 19.0% at 5 months before death, before increasing exponentially to 51.6% at 1 month before death. The median number of days in bed fluctuated within a narrow range of 3 to 7 from 24 months to 4 months before death, before increasing substantially to a high of 14 at 1 month before death. In the last 2 years of life, the burden of bed rest did not differ by age but was significantly greater in women than men. Among the conditions leading to death, the burden of bed rest was highest among persons dying from organ failure and cancer, lowest for sudden death, and intermediate for frailty, advanced dementia, and other conditions.
The burden of bed rest at the end of life is greater in women than men, does not differ by age, and is highest among persons dying from organ failure and cancer. The steep increases observed in the last 3 to 5 months of life suggest that taking to bed may be an indicator that death is approaching and should prompt discussions about referral to hospice among older persons with serious illness.
评估生命终末期“卧床”的时间进程,并确定其是否因年龄、性别和导致死亡的疾病而有所不同。
前瞻性纵向研究。
康涅狄格州大纽黑文。
共有 651 名来自社区生活的 754 名 70 岁以上的已故者。
在生命的最后 2 年中,每月确定卧床休息的发生情况和卧床休息的天数,这两个指标是卧床休息负担的衡量标准。卧床休息是指因疾病、伤害或其他问题而至少卧床半天。
卧床休息的发生率从死亡前 24 个月的 12.4%略有增加到死亡前 5 个月的 19.0%,然后呈指数增长到死亡前 1 个月的 51.6%。死亡前 24 个月至 4 个月期间,卧床休息的天数中位数在 3 至 7 天之间波动,然后在死亡前 1 个月大幅增加至 14 天的高位。在生命的最后 2 年中,卧床休息的负担与年龄无关,但女性明显大于男性。在导致死亡的疾病中,器官衰竭和癌症导致的卧床休息负担最高,猝死最低,衰弱、晚期痴呆症和其他疾病则处于中间。
生命终末期的卧床休息负担在女性中大于男性,与年龄无关,在因器官衰竭和癌症而死亡的人中最高。在生命的最后 3 至 5 个月观察到的急剧增加表明,卧床可能是死亡临近的一个指标,应促使对患有严重疾病的老年人进行临终关怀转诊的讨论。