Bonds D R, Crosby L O, Cheek T G, Hägerdal M, Gutsche B B, Gabbe S G
J Dev Physiol. 1986 Feb;8(1):49-54.
The Bohr Principle via continuous indirect calorimetry was used to estimate human fetal-placental unit metabolic rate in 12 normal women undergoing elective caesarean section under continuous lumbar epidural anaesthesia. Maternal oxygen consumption decreased after umbilical cord clamping and after placental removal. Fetal-placental unit oxygen consumption was 10.7 +/- 1.3 ml/min per kg (mean +/- SEM). Fetal oxygen consumption was 6.8 +/- 1.4 ml/min per kg. Placental oxygen consumption was 37 +/- 12 ml/min per kg. Fetal-placental unit carbon dioxide production was 9.2 +/- 1.2 ml/min per kg. These mean values agree favourably with measurements of uterine and fetal metabolism from other mammalian species. Maternal minute ventilation decreased with removal of the fetal-placental unit, and this decrease was found to be linearly related to the fetal-placental unit carbon dioxide production.
通过连续间接测热法的玻尔原理，对12名在连续腰段硬膜外麻醉下接受择期剖宫产的正常女性的胎儿 - 胎盘单位代谢率进行了估算。脐带钳夹后和胎盘取出后，母体耗氧量下降。胎儿 - 胎盘单位耗氧量为每千克体重10.7±1.3毫升/分钟（均值±标准误）。胎儿耗氧量为每千克体重6.8±1.4毫升/分钟。胎盘耗氧量为每千克体重37±12毫升/分钟。胎儿 - 胎盘单位二氧化碳生成量为每千克体重9.2±1.2毫升/分钟。这些均值与其他哺乳动物物种子宫和胎儿代谢的测量值非常吻合。随着胎儿 - 胎盘单位的取出，母体分钟通气量下降，并且发现这种下降与胎儿 - 胎盘单位二氧化碳生成量呈线性相关。
