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2
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SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children.SIAIP 立场文件:儿童抗生素和非甾体抗炎药激发挑战。
Ital J Pediatr. 2018 Dec 7;44(1):147. doi: 10.1186/s13052-018-0589-3.
2
The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria.欧洲过敏研究学会/过敏标准委员会/欧洲皮肤病学会/世界变态反应组织荨麻疹指南:定义、分类、诊断和管理。
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Drug-induced photosensitivity: Photoallergic and phototoxic reactions.药物性光敏反应:光变应性和光毒性反应。
Clin Dermatol. 2016 Sep-Oct;34(5):571-81. doi: 10.1016/j.clindermatol.2016.05.006. Epub 2016 May 20.
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Probiotics and refractory chronic spontaneous urticaria.益生菌与难治性慢性自发性荨麻疹
Eur Ann Allergy Clin Immunol. 2016 Sep;48(5):182-7.
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Consensus Conference on Clinical Management of pediatric Atopic Dermatitis.儿童特应性皮炎临床管理共识会议
Ital J Pediatr. 2016 Mar 2;42:26. doi: 10.1186/s13052-016-0229-8.
6
QUESTION 2: Does amoxicillin exposure increase the risk of rash in children with acute Epstein-Barr virus infection?问题2:阿莫西林暴露会增加急性爱泼斯坦-巴尔病毒感染儿童出现皮疹的风险吗?
Arch Dis Child. 2016 May;101(5):500-2. doi: 10.1136/archdischild-2015-310364. Epub 2016 Feb 18.
7
Use of probiotics in pediatric infectious diseases.益生菌在儿科感染性疾病中的应用。
Expert Rev Anti Infect Ther. 2015;13(12):1517-35. doi: 10.1586/14787210.2015.1096775. Epub 2015 Oct 23.
8
Approaches to the diagnosis and management of patients with a history of nonsteroidal anti-inflammatory drug-related urticaria and angioedema.非甾体抗炎药相关性荨麻疹和血管性水肿患者的诊断和管理方法。
J Allergy Clin Immunol. 2015 Aug;136(2):245-51. doi: 10.1016/j.jaci.2015.06.021.
9
Diagnostic accuracy of patch test in children with food allergy.斑贴试验对食物过敏儿童的诊断准确性。
Pediatr Allergy Immunol. 2015 Aug;26(5):416-22. doi: 10.1111/pai.12377. Epub 2015 May 11.
10
Demographic and clinical profiles in patients with acute urticaria.急性荨麻疹患者的人口统计学和临床特征。
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药物引起的轻度皮肤反应。

Mild cutaneous reactions to drugs.

作者信息

Crisafulli Giuseppe, Franceschini Fabrizio, Caimmi Silvia, Bottau Paolo, Liotti Lucia, Saretta Francesca, Bernardini Roberto, Cardinale Fabio, Mori Francesca, Caffarelli Carlo

机构信息

UO Allergologia, Dipartimento di Pediatria, Università di Messina, Italy.

出版信息

Acta Biomed. 2019 Jan 28;90(3-S):36-43. doi: 10.23750/abm.v90i3-S.8159.

DOI:10.23750/abm.v90i3-S.8159
PMID:30830060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6502176/
Abstract

Adverse reactions to drugs are not frequent in childhood. Cutaneous reactions are the most frequent in this age group. Mild cutaneous reactions are immediate or delayed adverse reactions that do not seriously compromise the clinical condition of children. The patients usually early improve and recover the state of health. Although it is difficult to define the prevalence accurately, we could affirm that the rate adverse reaction to drugs are often over estimated by both the families and the physicians. Therefore, children may be prone to loss of school days and inappropriate or sub-optimal treatments. However, the identification of a true adverse reaction to drugs allows adequate treatment and alert to further exposure to harmful drugs.

摘要

药物不良反应在儿童期并不常见。皮肤反应是该年龄组中最常见的。轻度皮肤反应是即刻或延迟的不良反应,不会严重影响儿童的临床状况。患者通常会早期好转并恢复健康状态。尽管很难准确界定其发生率,但我们可以肯定的是,家庭和医生往往都高估了药物不良反应的发生率。因此,儿童可能容易出现缺课以及接受不恰当或不理想的治疗。然而,识别真正的药物不良反应有助于进行适当治疗,并警惕再次接触有害药物。