Danielsson K, Evers H, Holmlund A, Kjellman O, Nordenram A, Persson N E
Int J Oral Maxillofac Surg. 1986 Apr;15(2):119-26. doi: 10.1016/s0300-9785(86)80131-4.
2 long-acting local anaesthetics, bupivacaine and etidocaine, have been compared to lidocaine with regard to effect during surgical removal of impacted mandibular third molars and effect upon the immediate postoperative pain. It can be concluded from this study that both bupivacaine and etidocaine as well as lidocaine were highly effective and without significant difference with regard to pain blocking during surgery. Both long-acting solutions were significantly superior to lidocaine in providing an extended duration of postoperative pain control. Comparing the 2 long-acting solutions, patients in the bupivacaine group had a significantly longer pain-free period than patients in the etidocaine group.
就拔除下颌阻生第三磨牙手术期间的效果以及对术后即刻疼痛的影响而言，已将两种长效局部麻醉药布比卡因和依替卡因与利多卡因进行了比较。从这项研究可以得出结论，布比卡因、依替卡因以及利多卡因在手术期间的疼痛阻滞方面均非常有效且无显著差异。两种长效溶液在提供延长的术后疼痛控制时间方面均显著优于利多卡因。比较这两种长效溶液，布比卡因组患者的无痛期明显长于依替卡因组患者。
