Sisk A L, Dionne R A, Wirdzek P R
J Oral Maxillofac Surg. 1984 Feb;42(2):84-8. doi: 10.1016/0278-2391(84)90316-1.
Etidocaine hydrochloride, an amide-type local anesthetic with prolonged duration of action, was evaluated and compared with a standard local anesthetic, lidocaine, to determine its efficacy as a local anesthetic and its effect on postoperative pain following removal of impacted third molars. The findings indicate that 1.5% etidocaine hydrochloride with 1:200,000 epinephrine, in comparison with 2% lidocaine hydrochloride with 1:100,000 epinephrine, suppresses the magnitude of postoperative pain, and results in anesthesia comparable with that obtained by lidocaine, but results in greater blood loss during surgery.
盐酸依替卡因是一种酰胺类长效局部麻醉药，对其进行了评估，并与标准局部麻醉药利多卡因进行比较，以确定其作为局部麻醉药的疗效以及对拔除阻生第三磨牙后术后疼痛的影响。研究结果表明，与含1:100,000肾上腺素的2%盐酸利多卡因相比，含1:200,000肾上腺素的1.5%盐酸依替卡因可减轻术后疼痛程度，产生与利多卡因相当的麻醉效果，但手术期间出血量更多。
