Kullaa-Mikkonen A, Sorvari T E
J Oral Pathol. 1986 Feb;15(2):93-7. doi: 10.1111/j.1600-0714.1986.tb00584.x.
In this study, scanning electron microscopy was used to describe the surface morphology of fissured tongue. Tissue samples from the anterior part of the tongue were taken from 15 patients with fissured tongue. The formalin-fixed samples were processed routinely for scanning electron microscopy. Typically, the surface of a fissured tongue was covered with hairless papillae of various sizes. The biggest papillae were larger than the body of a normal filiform papilla, and the apex was rounded and rough. On the other hand, some of these papillae had a few hairs and resembled normal filiform papillae, but were flatter. In addition some papillae formed only slight elevations on the tongue mucosa, which was smooth and contained some desquamating cells. The walls of the fissure found in macroscopical examination consisted of very low elevations of the smooth mucosa with some desquamating cells. At high magnification the superficial cells of the epithelium were polygonal. On their surface there were branching or parallel microplicae, which were often broken. Only occasionally superficial cells of the large papillae had a pitted appearance. The knob-like structures found among the microplicae and small cracks between the epithelial cells are discussed from the standpoint of the pathogenesis of fissured tongue.
在本研究中，使用扫描电子显微镜描述沟纹舌的表面形态。从15例沟纹舌患者的舌前部采集组织样本。将福尔马林固定的样本常规处理用于扫描电子显微镜检查。典型地，沟纹舌的表面覆盖有各种大小的无毛乳头。最大的乳头比正常丝状乳头的主体大，顶端呈圆形且粗糙。另一方面，其中一些乳头有几根毛发，类似于正常丝状乳头，但更扁平。此外，一些乳头仅在舌黏膜上形成轻微隆起，黏膜光滑且含有一些脱落细胞。宏观检查中发现的沟纹壁由带有一些脱落细胞的光滑黏膜的非常低的隆起组成。在高倍镜下，上皮的表层细胞呈多边形。在它们的表面有分支或平行的微褶，这些微褶经常断裂。仅偶尔大乳头的表层细胞有凹陷外观。从沟纹舌的发病机制角度讨论了在微褶之间发现的瘤状结构和上皮细胞之间的小裂缝。
