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用新型单环β-内酰胺类抗生素氨曲南和克林霉素治疗急性盆腔炎性疾病。

Treatment of acute pelvic inflammatory disease with aztreonam, a new monocyclic beta-lactam antibiotic, and clindamycin.

作者信息

Dodson M G, Faro S, Gentry L O

出版信息

Obstet Gynecol. 1986 May;67(5):657-62. doi: 10.1097/00006250-198605000-00010.

DOI:10.1097/00006250-198605000-00010
PMID:3083313
Abstract

Forty-two patients with acute pelvic inflammatory disease were treated using aztreonam, a monobactam, and clindamycin. Sixty-four percent of protocol patients were culture positive for Neisseria gonorrhoeae, and 26% had positive endometrial cultures for other organisms. Fifty-one percent of patients had ultrasound findings consistent with a pelvic abscess. One patient with a tuboovarian abscess palpable to the umbilicus became afebrile and improved on treatment, but ultimately was treated surgically. All other protocol patients responded rapidly to the aztreonam-clindamycin regime, giving a 97.7% cure rate.

摘要

42例急性盆腔炎患者接受了氨曲南(一种单环β-内酰胺类抗生素)和克林霉素治疗。64%的方案治疗患者淋病奈瑟菌培养呈阳性,26%的患者子宫内膜培养出其他病原体。51%的患者超声检查结果与盆腔脓肿相符。1例可触及至脐部的输卵管卵巢脓肿患者经治疗后退热且病情改善,但最终接受了手术治疗。所有其他方案治疗患者对氨曲南-克林霉素治疗方案反应迅速,治愈率达97.7%。

相似文献

1
Treatment of acute pelvic inflammatory disease with aztreonam, a new monocyclic beta-lactam antibiotic, and clindamycin.用新型单环β-内酰胺类抗生素氨曲南和克林霉素治疗急性盆腔炎性疾病。
Obstet Gynecol. 1986 May;67(5):657-62. doi: 10.1097/00006250-198605000-00010.
2
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Aztreonam plus clindamycin as therapy for pelvic infections in women.氨曲南加克林霉素用于治疗女性盆腔感染。
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A comparison of two antibiotic regimens for treatment of pelvic inflammatory disease.两种抗生素治疗方案用于盆腔炎治疗的比较。
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[Clinical evaluation of a combination therapy with aztreonam and clindamycin for severe infections in leukemia and related disorders].氨曲南与克林霉素联合治疗白血病及相关疾病严重感染的临床评估
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Quinolones for the treatment of Neisseria gonorrhoeae and Chlamydia trachomatis.用于治疗淋病奈瑟菌和沙眼衣原体的喹诺酮类药物。
Infect Dis Obstet Gynecol. 1993;1(2):108-13. doi: 10.1155/S1064744993000250.
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Optimum therapy for acute pelvic inflammatory disease.急性盆腔炎的最佳治疗方法。
Drugs. 1990 Apr;39(4):511-22. doi: 10.2165/00003495-199039040-00004.