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本文引用的文献

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Insular multiple sclerosis lesions are associated with erectile dysfunction.岛叶多发性硬化病灶与勃起功能障碍有关。
J Neurol. 2018 Apr;265(4):783-792. doi: 10.1007/s00415-018-8763-5. Epub 2018 Feb 1.
2
Lesion mapping of stroke-related erectile dysfunction.中风相关勃起功能障碍的病灶定位。
Brain. 2017 Jun 1;140(6):1706-1717. doi: 10.1093/brain/awx080.
3
Erectile dysfunction and cardiovascular disease.勃起功能障碍与心血管疾病
Arab J Urol. 2013 Sep;11(3):212-6. doi: 10.1016/j.aju.2013.03.003. Epub 2013 May 3.
4
The measurement properties of the five-item International Index of Erectile Function (IIEF-5): a Dutch validation study.五项国际勃起功能指数(IIEF-5)的测量特性:一项荷兰验证研究。
Andrology. 2015 Nov;3(6):1154-9. doi: 10.1111/andr.12112. Epub 2015 Oct 9.
5
Stroke in South Asia: a systematic review of epidemiologic literature from 1980 to 2010.南亚的脑卒中:1980 年至 2010 年流行病学文献的系统评价。
Neuroepidemiology. 2012;38(3):123-9. doi: 10.1159/000336230. Epub 2012 Mar 15.
6
Epidemiology and the global burden of stroke.流行病学与全球卒中负担。
World Neurosurg. 2011 Dec;76(6 Suppl):S85-90. doi: 10.1016/j.wneu.2011.07.023.
7
Erectile dysfunction and diabetes: a review of the current evidence-based medicine and a synthesis of the main available therapies.勃起功能障碍与糖尿病:当前循证医学证据的回顾及主要可用疗法的综合
Diabetes Metab. 2012 Feb;38(1):1-13. doi: 10.1016/j.diabet.2011.09.003. Epub 2011 Nov 4.
8
Stroke, obesity and gender: a review of the literature.中风、肥胖与性别:文献综述。
Maturitas. 2011 Jul;69(3):239-43. doi: 10.1016/j.maturitas.2011.04.010. Epub 2011 May 23.
9
The Mini-Mental State Examination and Montreal Cognitive Assessment in persons with mild subacute stroke: relationship to functional outcome.轻度亚急性脑卒中患者的简易精神状态检查和蒙特利尔认知评估:与功能结局的关系。
Arch Phys Med Rehabil. 2011 May;92(5):792-8. doi: 10.1016/j.apmr.2010.12.034.
10
Opposed hemispheric specializations for human hypersexuality and orgasm?人类性欲和性高潮是否存在对侧半球专门化?
Epilepsy Behav. 2011 May;21(1):12-9. doi: 10.1016/j.yebeh.2011.01.023. Epub 2011 Apr 8.

中风后患者左半球病变与勃起功能障碍之间的正相关关系。

Positive Correlation between Left Hemisphere Lesion and Erectile Dysfunction in Post-Stroke Patients.

作者信息

Purwata Thomas Eko, Andaka Dedy, Nuartha Aabn, Wiratni Candra, Sumada Ketut

机构信息

Department of Neurology, Faculty of Medicine, Udayana University, Sanglah Hospital, Bali, Indonesia.

Department of Neurology, Siloam Hospital, Bali, Indonesia.

出版信息

Open Access Maced J Med Sci. 2019 Feb 13;7(3):363-368. doi: 10.3889/oamjms.2019.125. eCollection 2019 Feb 15.

DOI:10.3889/oamjms.2019.125
PMID:30834002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6390166/
Abstract

BACKGROUND

Stroke is a serious health condition and the leading cause of disability, including erectile dysfunction (ED). The mechanisms and factors that predict ED in stroke are not fully elucidated. Several studies have shown a relationship between the location of the lesion in stroke with the onset of ED. The left hemispheric lesion was believed to disrupt the parasympathetic nervous system which is responsible for the regulation of erection. Stroke attack in this region therefore can be the underlying reason for ED. However, there are still contradictory findings in this area, and very few studies attempted to look at this problem, particularly among Asian male.

AIM

We would like to evaluate the association between left hemisphere lesion after ischemic stroke and the subsequent risk of developing ED.

METHODS

The study was conducted in the neurology polyclinic of Sanglah and Wangaya Hospital from February to August 2013. Subjects are all post-stroke patients who visited the neurology polyclinic of Sanglah and Wangaya Hospital that met inclusion and exclusion criteria.

RESULTS

There is a significant positive correlation (p < 0.05) between left hemisphere lesions and ED in stroke patients with a correlation coefficient (r) = 0.361 which means weak correlation and p = 0.032.

CONCLUSION

Left hemisphere lesions positively correlated with ED in stroke patients. Further longitudinal research is needed to see whether left hemisphere lesion in post-stroke patients is a risk factor for ED.

摘要

背景

中风是一种严重的健康状况,是导致残疾的主要原因,包括勃起功能障碍(ED)。中风中预测ED的机制和因素尚未完全阐明。几项研究表明,中风病灶的位置与ED的发生之间存在关联。据信,左半球病变会破坏负责勃起调节的副交感神经系统。因此,该区域的中风发作可能是ED的潜在原因。然而,这一领域仍存在相互矛盾的发现,很少有研究试图探讨这个问题,尤其是在亚洲男性中。

目的

我们希望评估缺血性中风后左半球病变与随后发生ED风险之间的关联。

方法

该研究于2013年2月至8月在桑格拉医院和瓦尼亚医院的神经科门诊进行。研究对象为所有前往桑格拉医院和瓦尼亚医院神经科门诊就诊且符合纳入和排除标准的中风后患者。

结果

中风患者中,左半球病变与ED之间存在显著正相关(p < 0.05),相关系数(r) = 0.361,意味着弱相关,p = 0.032。

结论

中风患者中左半球病变与ED呈正相关。需要进一步的纵向研究来观察中风后患者的左半球病变是否是ED的危险因素。