Purwata Thomas Eko, Andaka Dedy, Nuartha Aabn, Wiratni Candra, Sumada Ketut
Department of Neurology, Faculty of Medicine, Udayana University, Sanglah Hospital, Bali, Indonesia.
Department of Neurology, Siloam Hospital, Bali, Indonesia.
Open Access Maced J Med Sci. 2019 Feb 13;7(3):363-368. doi: 10.3889/oamjms.2019.125. eCollection 2019 Feb 15.
Stroke is a serious health condition and the leading cause of disability, including erectile dysfunction (ED). The mechanisms and factors that predict ED in stroke are not fully elucidated. Several studies have shown a relationship between the location of the lesion in stroke with the onset of ED. The left hemispheric lesion was believed to disrupt the parasympathetic nervous system which is responsible for the regulation of erection. Stroke attack in this region therefore can be the underlying reason for ED. However, there are still contradictory findings in this area, and very few studies attempted to look at this problem, particularly among Asian male.
We would like to evaluate the association between left hemisphere lesion after ischemic stroke and the subsequent risk of developing ED.
The study was conducted in the neurology polyclinic of Sanglah and Wangaya Hospital from February to August 2013. Subjects are all post-stroke patients who visited the neurology polyclinic of Sanglah and Wangaya Hospital that met inclusion and exclusion criteria.
There is a significant positive correlation (p < 0.05) between left hemisphere lesions and ED in stroke patients with a correlation coefficient (r) = 0.361 which means weak correlation and p = 0.032.
Left hemisphere lesions positively correlated with ED in stroke patients. Further longitudinal research is needed to see whether left hemisphere lesion in post-stroke patients is a risk factor for ED.
中风是一种严重的健康状况,是导致残疾的主要原因,包括勃起功能障碍(ED)。中风中预测ED的机制和因素尚未完全阐明。几项研究表明,中风病灶的位置与ED的发生之间存在关联。据信,左半球病变会破坏负责勃起调节的副交感神经系统。因此,该区域的中风发作可能是ED的潜在原因。然而,这一领域仍存在相互矛盾的发现,很少有研究试图探讨这个问题,尤其是在亚洲男性中。
我们希望评估缺血性中风后左半球病变与随后发生ED风险之间的关联。
该研究于2013年2月至8月在桑格拉医院和瓦尼亚医院的神经科门诊进行。研究对象为所有前往桑格拉医院和瓦尼亚医院神经科门诊就诊且符合纳入和排除标准的中风后患者。
中风患者中,左半球病变与ED之间存在显著正相关(p < 0.05),相关系数(r) = 0.361,意味着弱相关,p = 0.032。
中风患者中左半球病变与ED呈正相关。需要进一步的纵向研究来观察中风后患者的左半球病变是否是ED的危险因素。