从一名患有胃溃疡的越南患者分离出的幽门螺杆菌GD63菌株的全基因组序列
Complete Genome Sequence of Helicobacter pylori Strain GD63, Isolated from a Vietnamese Patient with a Gastric Ulcer.
作者信息
Nguyen-Hoang Thien-Phuc, Nguyen Hoa Trang, Nguyen Tan-Huy, Baker Stephen, Rahman Motiur, Nguyen Thuy-Vy
机构信息
Department of Genetics, Faculty of Biology and Biotechnology, University of Science, VNU-HCM, Ho Chi Minh City, Vietnam.
Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
出版信息
Microbiol Resour Announc. 2019 Feb 21;8(8). doi: 10.1128/MRA.01412-18. eCollection 2019 Feb.
Abstract
We present here the first complete genome sequence of Helicobacter pylori strain GD63, isolated from a 72-year-old male Vietnamese patient with a chronic gastric ulcer. The genome consists of a 1.6-Mbp chromosome and an 8.9-kbp plasmid. The strain is pathogenicity island (PAI) and VacA positive and belongs to the hpEAsia lineage.
摘要
我们在此展示幽门螺杆菌菌株GD63的首个完整基因组序列，该菌株是从一名患有慢性胃溃疡的72岁越南男性患者体内分离得到的。该基因组由一条1.6兆碱基对的染色体和一个8.9千碱基对的质粒组成。该菌株致病性岛（PAI）和空泡毒素A（VacA）呈阳性，属于hpEAsia谱系。
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