Kaga Naoyuki, Toshima Hirokazu, Nagano-Takebe Futami, Hashimoto Masanori, Nezu Takashi, Yokoyama Atsuro, Endo Kazuhiko, Kaga Masayuki
Department of Oral Rehabilitation, Section of Fixed Prosthodontics, Fukuoka Dental College, Fukuoka, Japan,
Department of Oral Rehabilitation, Division of Biomaterials and Bio-engineering, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Am J Dent. 2019 Feb;32(1):27-30.
To evaluate the inhibitory effect of a surface pre-reacted glass-ionomer (S-PRG) filler-containing tooth-coating material on enamel demineralization. The outer surface of the S-PRG filler is in a state in which ions are readily released.
Human enamel blocks were incubated in lactic acid solution (pH 4.0) with and without a disk (n=6) made of the cured tooth-coating material. Test solutions were changed every 24 hours and incubation was continued for 4 days. The pH and amount of fluoride released were measured with an electrode and ion meter, respectively. The concentrations of ions (aluminum, boron, calcium, phosphorus, silicon, sodium, and strontium) were measured by inductively coupled plasma atomic emission spectroscopy. The surface of the enamel block was observed with a scanning electron microscope.
Enamel demineralization was not observed in an enamel block incubated with a disk of the tooth-coating material. Ions released from S-PRG filler had an acid buffering action in the low pH lactic acid solution. However, in the enamel block-only solution showing high levels of calcium ion release, the degree of demineralization was correlated with morphological changes of the enamel surface.
Due to the buffering effects of the pre-reacted glass-ionomer surface by ion release, the S-PRG filler-containing tooth-coating material inhibited enamel demineralization by neutralizing the acidic environment at an early time point.
评估含表面预反应玻璃离子（S-PRG）填料的牙齿涂层材料对牙釉质脱矿的抑制作用。S-PRG填料的外表面处于易于释放离子的状态。
将人类牙釉质块置于乳酸溶液（pH 4.0）中，分别加入和不加入由固化牙齿涂层材料制成的圆盘（n = 6）。每24小时更换一次测试溶液，并持续孵育4天。分别使用电极和离子计测量pH值和氟释放量。通过电感耦合等离子体原子发射光谱法测量离子（铝、硼、钙、磷、硅、钠和锶）的浓度。用扫描电子显微镜观察牙釉质块的表面。
在与牙齿涂层材料圆盘一起孵育的牙釉质块中未观察到牙釉质脱矿。从S-PRG填料释放的离子在低pH乳酸溶液中具有酸缓冲作用。然而，在仅含牙釉质块的溶液中，钙离子释放水平较高，脱矿程度与牙釉质表面的形态变化相关。
由于预反应玻璃离子表面通过离子释放产生缓冲作用，含S-PRG填料的牙齿涂层材料通过在早期中和酸性环境来抑制牙釉质脱矿。
