1 Palliative Care, OhioHealth Grant Medical Center, Columbus, Ohio.
2 Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio.
J Palliat Med. 2019 Jul;22(7):790-796. doi: 10.1089/jpm.2018.0292. Epub 2019 Mar 4.
The impact of specialty pediatric palliative care (PPC) on intensive care unit (ICU) length of stay for children is unclear. To estimate the impact of PPC consultation by analyzing ICU stay as a dynamic outcome over the course of hospitalization. Retrospective cohort study of children hospitalized with diagnoses suggested as referral triggers for PPC at a large academic children's hospital. We assessed ICU stay according to PPC consultation and, using a patient-day analysis, applied multivariable mixed effects logistic regression to predict the odds of being in the ICU on a given day. The analytic sample included 777 admissions (11,954 hospital days), of which 100 admissions (13%) included PPC consultation. Principal patient demographics were age 8 ± 6 years, 55% male sex, 71% white race, and 52% commercial insurance. Cardiac diagnoses were most frequent (29%) followed by gastrointestinal (22%) and malignant (20%) conditions. Although total ICU stay was longer for admissions, including PPC consultation (compared to admissions where PPC was not consulted), the odds of being in the ICU on a given day were reduced by 79% after PPC consultation (odds ratio [OR] = 0.21; 95% confidence interval [CI]: 0.13-0.34; < 0.001) for children with cancer and 85% (OR = 0.15; 95% CI: 0.08-0.26; < 0.001) for children with nononcologic conditions. Among children hospitalized with a diagnosis deemed eligible for specialty PPC, the likelihood of being in the ICU on a given day was strongly reduced after PPC consultation, supporting the value of PPC.
儿科专科姑息治疗(PPC)对儿童重症监护病房(ICU)住院时间的影响尚不清楚。本研究旨在通过分析住院期间 ICU 住院时间这一动态结局,评估 PPC 咨询对 ICU 住院时间的影响。
这是一项回顾性队列研究,纳入了在一家大型学术儿童医院因疑似 PPC 转诊指征而住院的患儿。根据 PPC 咨询情况评估 ICU 住院时间,并采用患者日分析,应用多变量混合效应逻辑回归预测某一天入住 ICU 的概率。
分析样本包括 777 例住院(11954 天),其中 100 例(13%)接受了 PPC 咨询。主要患者人口统计学特征为年龄 8±6 岁,55%为男性,71%为白人,52%为商业保险。最常见的诊断是心脏疾病(29%),其次是胃肠道疾病(22%)和恶性疾病(20%)。尽管包括 PPC 咨询的住院患儿的 ICU 总住院时间更长(与未咨询 PPC 的住院患儿相比),但 PPC 咨询后,癌症患儿 ICU 住院的概率降低了 79%(比值比 [OR] = 0.21;95%置信区间 [CI]:0.13-0.34; < 0.001),非肿瘤患儿 ICU 住院的概率降低了 85%(OR = 0.15;95% CI:0.08-0.26; < 0.001)。
对于因诊断符合接受专科 PPC 资格的住院患儿,PPC 咨询后 ICU 住院的可能性显著降低,这支持了 PPC 的价值。