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经皮射频消融术后骨样骨瘤影像学表现的治疗相关性改变。

Treatment-related alterations of imaging findings in osteoid osteoma after percutaneous radiofrequency ablation.

机构信息

Gazi University Faculty of Medicine, Department of Radiology, Gazi Hastanesi, Besevler, 06500, Ankara, Turkey.

出版信息

Skeletal Radiol. 2019 Nov;48(11):1697-1703. doi: 10.1007/s00256-019-03185-1. Epub 2019 Mar 6.

DOI:10.1007/s00256-019-03185-1
PMID:30840098
Abstract

OBJECTIVES

We aimed to report the long-term outcomes of osteoid osteoma patients and to determine CT and dynamic contrast-enhanced MR imaging characteristics of radiofrequency ablation (RFA) treatment related changes of osteoid osteoma between follow-up periods.

MATERIALS AND METHODS

Thirty patients (seven female, 23 male) who underwent CT-guided RFA of osteoid osteoma were included. Follow-up imaging examinations were divided into two subgroups; first (1-3 months) and second (> 6 months) periods. Nidus size, calcification, cortical thickening, maximum signal intensity (SImax), time of SImax (Tmax), slope of signal intensity-time (SIT) curves were noted. CT and dynamic MR imaging findings were compared between follow-up periods.

RESULTS

Clinical success rate was 100%. The mean of OO nidi size was 5.85 ± 1.98 mm before treatment. There was a significant difference for OO nidi sizes between pretreatment and second follow-up period examinations (p = 0.002). SImax and slope of SIT curves of all patients (100%) showed decrease on follow-up MRIs. There was a significant decrease for SImax values between pretreatment and second follow-up period. There was a significant decrease for slope of SIT curves between pretreatment and both follow-up periods.

CONCLUSIONS

RFA is an effective and safe treatment choice for osteoid osteomas. On follow-up imaging, slope of SIT curve and Tmax have the most important positive predictive value for long-term outcomes and single dynamic contrast-enhanced MRI within first 3 months after treatment may be sufficient for symptom-free patients.

摘要

目的

我们旨在报告骨样骨瘤患者的长期结果,并确定 CT 和动态对比增强磁共振成像(DCE-MRI)在随访期间对骨样骨瘤射频消融(RFA)治疗相关变化的特征。

材料与方法

共纳入 30 名接受 CT 引导下 RFA 治疗骨样骨瘤的患者(7 名女性,23 名男性)。随访影像学检查分为两个亚组:第一亚组(1-3 个月)和第二亚组(>6 个月)。记录病灶大小、钙化、皮质增厚、最大信号强度(SImax)、达到 SImax 的时间(Tmax)、信号强度时间(SIT)曲线斜率。比较随访期间的 CT 和 DCE-MRI 表现。

结果

临床成功率为 100%。治疗前骨样骨瘤平均病灶大小为 5.85±1.98mm。治疗前与第二随访期的病灶大小有显著差异(p=0.002)。所有患者(100%)的 SImax 和 SIT 曲线斜率在随访 MRI 上均显示下降。SImax 值在治疗前与第二随访期之间有显著下降。SIT 曲线斜率在治疗前与两个随访期之间均有显著下降。

结论

RFA 是治疗骨样骨瘤的有效且安全的选择。在随访影像学上,SIT 曲线斜率和 Tmax 对长期结果具有最重要的阳性预测价值,且治疗后 3 个月内的单次 DCE-MRI 可能足以满足无症状患者的需求。

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