Gazi University Faculty of Medicine, Department of Radiology, Gazi Hastanesi, Besevler, 06500, Ankara, Turkey.
Skeletal Radiol. 2019 Nov;48(11):1697-1703. doi: 10.1007/s00256-019-03185-1. Epub 2019 Mar 6.
We aimed to report the long-term outcomes of osteoid osteoma patients and to determine CT and dynamic contrast-enhanced MR imaging characteristics of radiofrequency ablation (RFA) treatment related changes of osteoid osteoma between follow-up periods.
Thirty patients (seven female, 23 male) who underwent CT-guided RFA of osteoid osteoma were included. Follow-up imaging examinations were divided into two subgroups; first (1-3 months) and second (> 6 months) periods. Nidus size, calcification, cortical thickening, maximum signal intensity (SImax), time of SImax (Tmax), slope of signal intensity-time (SIT) curves were noted. CT and dynamic MR imaging findings were compared between follow-up periods.
Clinical success rate was 100%. The mean of OO nidi size was 5.85 ± 1.98 mm before treatment. There was a significant difference for OO nidi sizes between pretreatment and second follow-up period examinations (p = 0.002). SImax and slope of SIT curves of all patients (100%) showed decrease on follow-up MRIs. There was a significant decrease for SImax values between pretreatment and second follow-up period. There was a significant decrease for slope of SIT curves between pretreatment and both follow-up periods.
RFA is an effective and safe treatment choice for osteoid osteomas. On follow-up imaging, slope of SIT curve and Tmax have the most important positive predictive value for long-term outcomes and single dynamic contrast-enhanced MRI within first 3 months after treatment may be sufficient for symptom-free patients.
我们旨在报告骨样骨瘤患者的长期结果,并确定 CT 和动态对比增强磁共振成像(DCE-MRI)在随访期间对骨样骨瘤射频消融(RFA)治疗相关变化的特征。
共纳入 30 名接受 CT 引导下 RFA 治疗骨样骨瘤的患者(7 名女性,23 名男性)。随访影像学检查分为两个亚组:第一亚组(1-3 个月)和第二亚组(>6 个月)。记录病灶大小、钙化、皮质增厚、最大信号强度(SImax)、达到 SImax 的时间(Tmax)、信号强度时间(SIT)曲线斜率。比较随访期间的 CT 和 DCE-MRI 表现。
临床成功率为 100%。治疗前骨样骨瘤平均病灶大小为 5.85±1.98mm。治疗前与第二随访期的病灶大小有显著差异(p=0.002)。所有患者(100%)的 SImax 和 SIT 曲线斜率在随访 MRI 上均显示下降。SImax 值在治疗前与第二随访期之间有显著下降。SIT 曲线斜率在治疗前与两个随访期之间均有显著下降。
RFA 是治疗骨样骨瘤的有效且安全的选择。在随访影像学上,SIT 曲线斜率和 Tmax 对长期结果具有最重要的阳性预测价值,且治疗后 3 个月内的单次 DCE-MRI 可能足以满足无症状患者的需求。