Mansour H, Brun-Pascaud M, Gougerot-Pocidalo M A, Pocidalo J J
C R Acad Sci III. 1986;302(7):247-9.
Inducers of cytochrome P450-linked mono-oxygenases increase the normobaric oxygen tolerance of the adult rat. Pulmonary inducers, as 3-methylcholanthrene and beta-naphthoflavone permit the rat survival and simultaneously a decrease of pulmonary edema. Phenobarbital, an hepatic inducer had lesser effects both on survival rate and on pulmonary and lymphoïd oxygen toxicity.
细胞色素P450相关单加氧酶的诱导剂可提高成年大鼠的常压耐氧能力。肺部诱导剂，如3-甲基胆蒽和β-萘黄酮可使大鼠存活，同时减轻肺水肿。肝诱导剂苯巴比妥对存活率以及肺部和淋巴组织的氧毒性影响较小。
