Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing, China.
The State Key Laboratory of Turbulence and Complex Systems, College of Engineering, Peking University, Beijing, China.
PLoS One. 2019 Mar 6;14(3):e0212943. doi: 10.1371/journal.pone.0212943. eCollection 2019.
The development of new signal systems for electrical biosensors could provide exciting new opportunities for biomedical analysis, pollutant monitoring, and explosive detection. The signal systems for commercial portable sensors involve the integration of a battery and a circuit conditioning system to power an amperometric biosensor. However, this increases the size and complexity of the entire system. In this study, we develop a simple amperometric biosensor that is directly powered by a button cell battery for the detection of lactate. A two-electrode sensing transducer was printed on cardboard or integrated on a ring. It was directly powered by a button cell battery, and connected to a multimeter for current measurement. This sensor showed a sensitive detection range of 0.04762-9.21429 mM and short measuring time of 2 min. These results show that this system can achieve an excellent sensing performance, and the construction of this new sensing system directly powered by a button cell battery offers a new method for further developing a wide range of miniaturized, flexible, portable, or wearable sensing systems, and these could be used in detecting various analytes that are important in medical diagnosis and environmental monitoring.
新的电生物传感器信号系统的发展可为生物医学分析、污染物监测和爆炸物检测提供令人兴奋的新机会。商业便携式传感器的信号系统涉及电池和电路调节系统的集成，以给电流型生物传感器供电。然而，这增加了整个系统的尺寸和复杂性。在这项研究中，我们开发了一种简单的电流型生物传感器，可直接由纽扣电池供电，用于检测乳酸。两个电极的传感转换器被打印在纸板上或集成在一个环上。它直接由纽扣电池供电，并连接到一个万用表进行电流测量。该传感器显示出 0.04762-9.21429mM 的灵敏检测范围和 2 分钟的短测量时间。这些结果表明，该系统可以实现出色的传感性能，这种由纽扣电池直接供电的新型传感系统的构建为进一步开发各种小型化、灵活化、便携式或可穿戴式传感系统提供了一种新方法，这些系统可用于检测在医学诊断和环境监测中非常重要的各种分析物。
