Department of NanoEngineering, University of California, San Diego , La Jolla, California 92093, United States.
ACS Sens. 2017 Oct 27;2(10):1531-1538. doi: 10.1021/acssensors.7b00603. Epub 2017 Oct 11.
This work describes a wireless wearable ring-based multiplexed chemical sensor platform for rapid electrochemical monitoring of explosive and nerve-agent threats in vapor and liquid phases. The ring-based sensor system consists of two parts: a set of printed electrochemical sensors and a miniaturized electronic interface, based on a battery-powered stamp-size potentiostat, for signal processing and wireless transmission of data. A wide range of electrochemical capabilities have thus been fully integrated into a 3D printed compact ring structure, toward performing fast square-wave voltammetry and chronoamperometric analyses, along with interchangeable screen-printed sensing electrodes for the rapid detection of different chemical threats. High analytical performance is demonstrated despite the remarkable miniaturization and integration of the ring system. The attractive capabilities of the wearable sensor ring system have been demonstrated for sensitive and rapid voltammetric and amperometric monitoring of nitroaromatic and peroxide explosives, respectively, along with amperometric biosensing of organophosphate (OP) nerve agents. Such ability of the miniaturized wearable sensor ring platform to simultaneously detect multiple chemical threats in both liquid and vapor phases and alert the wearer of such hazards offers considerable promise for meeting the demands of diverse defense and security scenarios.
这项工作描述了一种基于无线可穿戴环的多路复用化学传感器平台，用于快速电化学监测蒸气相和液相中的爆炸物和神经毒剂威胁。基于环的传感器系统由两部分组成：一组印刷电化学传感器和一个基于电池供电邮票大小的电位计的小型化电子接口，用于信号处理和数据的无线传输。因此，各种电化学功能已完全集成到 3D 打印的紧凑环结构中，以进行快速方波伏安法和计时电流分析，以及用于快速检测不同化学威胁的可互换丝网印刷感测电极。尽管环系统实现了显著的小型化和集成，但仍展示出了高分析性能。可穿戴传感器环系统的诱人功能已通过对硝基芳烃和过氧化物爆炸物的灵敏和快速伏安法和安培法监测以及对有机磷 (OP) 神经毒剂的安培生物传感得到了证明。这种小型化可穿戴传感器环平台同时检测液体和蒸气相中的多种化学威胁并向佩戴者发出此类危险警报的能力为满足各种防御和安全场景的需求提供了很大的希望。
