Logar C, Grabmair W, Reinbacher N, Ladurner G
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1986 Mar;17(1):37-40.
In 31 patients with tranquilizer-and 13 patients with drug abuse the character and extent of changes in EEG during withdrawal period were studied and the influence of additional abuse of alcohol or barbiturates was investigated. The EEG showed pathological results in 22 patients (50%). Generalised spike activity was dominant, which was found more often in patients with tranquilizer abuse (35%) than in patients with drug abuse (15%). In patients with abuse of tranquilizers and additional alcoholism pathological EEGs were found more often (65%) than in the remaining patients (36%). Also in patients with additional abuse of barbiturates pathological EEGs (67%) were found more often. In patients with drug abuse with or without additional abuse of alcohol or barbiturates there was no difference between the number of normal and pathological EEGs. In patients with longer persistence of the tranquilizer abuse the number of pathological EEGs increased. Controls of the EEG revealed with increasing time interval an increasing number of normalised EEGs especially in patients without alcoholism of barbiturate abuse. Therefore the EEG revealed functional disturbances in the withdrawal period after abuse of tranquilizers or drugs which were more pronounced in patients with additional abuse or alcohol or barbiturates.
对31例使用镇静剂的患者和13例药物滥用患者在戒断期脑电图变化的特征及程度进行了研究，并调查了额外滥用酒精或巴比妥类药物的影响。脑电图检查结果显示，22例患者（50%）存在病理改变。以广泛性棘波活动为主，在使用镇静剂滥用的患者中更为常见（35%），而在药物滥用患者中为（15%）。在滥用镇静剂并伴有酒精中毒的患者中，病理性脑电图的发生率（65%）高于其余患者（36%）。同样，在额外滥用巴比妥类药物的患者中，病理性脑电图的发生率也更高（67%）。在有或没有额外滥用酒精或巴比妥类药物的药物滥用患者中，正常脑电图和病理性脑电图的数量没有差异。在镇静剂滥用持续时间较长的患者中，病理性脑电图的数量增加。脑电图检查显示，随着时间间隔的增加，脑电图正常化的数量越来越多，尤其是在没有酒精中毒或巴比妥类药物滥用的患者中。因此，脑电图显示在滥用镇静剂或药物后的戒断期存在功能障碍，在额外滥用酒精或巴比妥类药物的患者中更为明显。
