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系统动力学方法在理解环境危害暴露导致累积健康风险中的应用。

The utility of a system dynamics approach for understanding cumulative health risk from exposure to environmental hazards.

机构信息

Department of Preventive Medicine & Community Health, University of Texas Medical Branch, 301 University Blvd. Route 1153, Galveston, TX 77555-1153, USA; Center in Environmental Toxicology, University of Texas Medical Branch, Galveston, TX, USA.

Department of Management, California State University, Chico, CA, USA.

出版信息

Environ Res. 2019 May;172:462-469. doi: 10.1016/j.envres.2019.02.039. Epub 2019 Feb 27.

DOI:10.1016/j.envres.2019.02.039
PMID:30844571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6755670/
Abstract

The potential of system dynamics modeling to advance our understanding of cumulative risk in the service of optimal health is discussed. The focus is on exploring system dynamics modeling as a systems science methodology that can provide a framework for examining the complexity of real-world social and environmental exposures among populations-particularly those exposed to multiple disparate sources of risk. The discussion also examines how system dynamics modeling can engage a diverse body of key stakeholders throughout the modeling process, promoting the collective assessment of assumptions and systematic gathering of critical data. Though not a panacea, system dynamics modeling provides a promising methodology to complement traditional research methods in understanding cumulative health effects from exposure to multiple environmental and social stressors.

摘要

本文探讨了系统动力学建模在增进我们对累积风险的理解方面的潜力,以促进最佳健康。重点是探索系统动力学建模作为一种系统科学方法,它可以为研究人群中现实世界的社会和环境暴露的复杂性提供一个框架,特别是那些面临多种不同风险源的人群。本文还探讨了系统动力学建模如何在建模过程中吸引不同的主要利益相关者,促进对假设的集体评估和对关键数据的系统收集。尽管不是万无一失的方法,但系统动力学建模为理解多种环境和社会压力源对健康的累积影响提供了一种有前途的方法,可作为传统研究方法的补充。

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引用本文的文献

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Making the invisible visible: Using a qualitative system dynamics model to map disparities in cumulative environmental stressors and children's neurodevelopment.使无形可见:利用定性系统动力学模型映射累积环境压力源与儿童神经发育的差异。
Environ Res. 2023 Mar 15;221:115295. doi: 10.1016/j.envres.2023.115295. Epub 2023 Jan 18.
2
Defining and Intervening on Cumulative Environmental Neurodevelopmental Risks: Introducing a Complex Systems Approach.定义和干预累积性环境神经发育风险:引入复杂系统方法。
Environ Health Perspect. 2021 Mar;129(3):35001. doi: 10.1289/EHP7333. Epub 2021 Mar 10.
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Rural-urban differences in estimated life expectancy associated with neighborhood-level cumulative social and environmental determinants.城乡间预期寿命的差异与邻里层面的累积社会和环境决定因素有关。
Prev Med. 2020 Oct;139:106214. doi: 10.1016/j.ypmed.2020.106214. Epub 2020 Jul 18.

本文引用的文献

1
Cumulative risk assessment lessons learned: a review of case studies and issue papers.累积风险评估的经验教训:案例研究与问题文件综述
Chemosphere. 2015 Feb;120:697-705. doi: 10.1016/j.chemosphere.2014.10.030. Epub 2014 Nov 6.
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Stressful early life experiences and immune dysregulation across the lifespan.一生中压力大的早期生活经历和免疫失调。
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Discovering how environmental exposures alter genes could lead to new treatments for chronic illnesses.发现环境暴露如何改变基因可能会为慢性疾病的新治疗方法提供线索。
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