Sabin Vaccine Institute, Washington, District of Columbia.
Clin Infect Dis. 2019 Mar 7;68(Suppl 2):S161-S164. doi: 10.1093/cid/ciy1117.
Typhoid became a low priority on the global public health agenda when it was largely eliminated from developed countries in the 1940s. However, communities in South Asia and sub-Saharan Africa continue to bear the brunt of the disease burden. One strategy to increase attention and coordinate action is the creation of a coalition to act as a steward for typhoid. The Coalition against Typhoid (CaT) was created in 2010 with the mission of preventing typhoid among vulnerable populations through research, education, and advocacy. CaT successfully raised the profile of typhoid through convening the community with a biennial international conference that has experienced growing participation, disseminating data and news through a website and newsletter with increasing readership, and advocating through social media and a blog reaching a diverse audience. In 2017, CaT joined forces with the Typhoid Vaccine Acceleration Consortium to "Take on Typhoid," combining advocacy and communications efforts to mobilize researchers, clinicians, and decision makers at the global, regional, and local levels to introduce the new typhoid conjugate vaccine. As a result, the knowledge base, political will, and momentum are increasingly in place to implement prevention and control interventions including the typhoid conjugate vaccine in the poor communities that have historically been left behind.
当伤寒在 20 世纪 40 年代从发达国家基本消除时，它在全球公共卫生议程上的优先级降低了。然而，南亚和撒哈拉以南非洲的社区仍在承受着疾病负担的冲击。一个增加关注和协调行动的策略是创建一个联盟，作为伤寒的管理者。抗伤寒联盟（CaT）于 2010 年成立，使命是通过研究、教育和宣传来预防弱势群体中的伤寒。CaT 通过两年一次的国际会议召集社区，成功地提高了伤寒的知名度，该会议的参与人数不断增加，通过一个网站和通讯来传播数据和新闻，读者人数也在不断增加，并通过社交媒体和博客向不同的受众进行宣传。2017 年，CaT 与伤寒疫苗加速联盟联手“应对伤寒”，将宣传和传播工作结合起来，动员全球、区域和地方各级的研究人员、临床医生和决策者引入新的伤寒结合疫苗。因此，知识库、政治意愿和动力越来越强，越来越有能力在历史上被忽视的贫困社区实施预防和控制干预措施，包括伤寒结合疫苗。
