Murata Hiroaki, Imai Kan, Nakagawa Kazuya, Nishigaki Yasunori
Department of Orthopaedics, Matsushita Memorial Hospital, Moriguchi, Osaka 570-8540, Japan.
Mol Clin Oncol. 2019 Mar;10(3):366-370. doi: 10.3892/mco.2019.1798. Epub 2019 Jan 9.
Collagenous fibroma arising from the subacromial region is extremely rare. It is important to distinguish collagenous fibroma from other fibrous tumors including desmoid tumors, to differentiate between the prognoses and management strategies, including surgical treatment. The present case report describes the case of a 42-year-old man with a collagenous fibroma of the subacromial region. He received a follow-up examination following treatment for osteosarcoma. Positron emission tomography (PET) scans used to assess for metastatic lesions indicated uptake in his left shoulder. The maximum standardized uptake value was 2.4. Magnetic resonance imaging demonstrated iso-intensity to muscle on T1-weighted images and iso-intensity with slightly high intensity on T2-weighted images. Post-contrast fat-suppressed magnetic resonance images indicated slightly heterogeneous enhancement of the lesion. There were no notable results from X-rays, bone scintigraphy and thallium-201 scintigraphy. Histological examination revealed collagenous fibroma. To the best of our knowledge, the present case is only the second incidence of collagenous fibroma arising from the subacromial region, and the first description of thallium-201 scintigraphy and PET scans in collagenous fibroma. The multimodal radiological data of this case may be useful for assisting in the differentiation of fibrous tumor types, including collagenous fibroma.
起源于肩峰下区域的胶原纤维瘤极为罕见。将胶原纤维瘤与包括硬纤维瘤在内的其他纤维性肿瘤区分开来，对于区分预后和制定包括手术治疗在内的管理策略至关重要。本病例报告描述了一名42岁男性患有肩峰下区域胶原纤维瘤的病例。他在接受骨肉瘤治疗后接受了随访检查。用于评估转移灶的正电子发射断层扫描（PET）显示其左肩有摄取。最大标准化摄取值为2.4。磁共振成像显示在T1加权图像上与肌肉等信号，在T2加权图像上呈等信号并伴有轻度高信号。增强后脂肪抑制磁共振图像显示病变有轻度不均匀强化。X线、骨闪烁显像和铊-201闪烁显像均无明显结果。组织学检查显示为胶原纤维瘤。据我们所知，本病例是肩峰下区域起源的胶原纤维瘤的第二例报道，也是首例关于铊-201闪烁显像和PET扫描在胶原纤维瘤中的描述。该病例的多模态放射学数据可能有助于辅助鉴别包括胶原纤维瘤在内的纤维性肿瘤类型。
