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基于奥沙利铂的化疗所致外周肝窦阻塞综合征

Peripheral hepatic sinusoidal obstruction syndrome due to oxaliplatin-based chemotherapy.

作者信息

Kobayashi Shinichiro, Okudaira Sadayuki, Kobayashi Kazuma, Kanetaka Kengo, Eguchi Susumu

机构信息

Department of Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.

Okudaira Clinic Nagasaki Japan.

出版信息

Clin Case Rep. 2019 Jan 9;7(2):394-396. doi: 10.1002/ccr3.1935. eCollection 2019 Feb.

DOI:10.1002/ccr3.1935
PMID:30847217
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6389491/
Abstract

Hepatic sinusoidal obstruction syndrome during oxaliplatin-based chemotherapy has been shown to be associated with severe steatohepatitis. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging may identify various features of hepatic sinusoidal obstruction syndrome, even when the lesion cannot be differentiated from sinusoidal obstruction syndrome by other imaging tools.

摘要

基于奥沙利铂的化疗期间发生的肝窦阻塞综合征已被证明与严重脂肪性肝炎相关。钆塞酸二钠增强磁共振成像可识别肝窦阻塞综合征的各种特征，即使在病变无法通过其他成像工具与窦状隙阻塞综合征区分开来时也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/4659ac1daebe/CCR3-7-394-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/7110ea78f4f8/CCR3-7-394-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/de4f06139c5c/CCR3-7-394-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/f14fd8226f2c/CCR3-7-394-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/ad7b8c8255af/CCR3-7-394-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/4659ac1daebe/CCR3-7-394-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/7110ea78f4f8/CCR3-7-394-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/de4f06139c5c/CCR3-7-394-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/f14fd8226f2c/CCR3-7-394-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/ad7b8c8255af/CCR3-7-394-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e47/6389491/4659ac1daebe/CCR3-7-394-g005.jpg

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本文引用的文献

1
Oxaliplatin-induced hepatic sinusoidal obstruction syndrome in a patient with gastric cancer: A case report.奥沙利铂诱发胃癌患者肝窦阻塞综合征：一例报告
Mol Clin Oncol. 2018 Mar;8(3):453-456. doi: 10.3892/mco.2017.1540. Epub 2017 Dec 18.
2
Oxaliplatin-induced sinusoidal obstruction syndrome mimicking metastatic colon cancer in the liver.奥沙利铂诱导的肝窦阻塞综合征酷似肝脏转移性结肠癌。
Oncol Lett. 2016 Apr;11(4):2861-2864. doi: 10.3892/ol.2016.4286. Epub 2016 Feb 29.
3
Hepatic sinusoidal obstruction associated with S-1 plus cisplatin chemotherapy for highly advanced gastric cancer with paraaortic lymph node metastases: report of a case.
S-1联合顺铂化疗治疗伴有腹主动脉旁淋巴结转移的晚期胃癌相关的肝窦阻塞综合征：病例报告
Clin J Gastroenterol. 2012 Oct;5(5):341-6. doi: 10.1007/s12328-012-0333-2. Epub 2012 Sep 18.
4
Nodular Regenerative Hyperplasia in Patients Undergoing Liver Resection for Colorectal Metastases After Chemotherapy: Risk Factors, Preoperative Assessment and Clinical Impact.化疗后接受肝切除治疗结直肠癌转移患者的结节性再生性增生：危险因素、术前评估及临床影响
Ann Surg Oncol. 2015 Dec;22(13):4149-57. doi: 10.1245/s10434-015-4533-0. Epub 2015 Apr 7.
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Sinusoidal obstruction syndrome after oxaliplatin-based chemotherapy.基于奥沙利铂的化疗后窦性阻塞综合征
Clin Mol Hepatol. 2014 Mar;20(1):81-4. doi: 10.3350/cmh.2014.20.1.81.
6
Accuracy of gadoxetic acid-enhanced magnetic resonance imaging for the diagnosis of sinusoidal obstruction syndrome in patients with chemotherapy-treated colorectal liver metastases.钆塞酸增强磁共振成像诊断化疗治疗结直肠癌肝转移患者的窦阻塞综合征的准确性。
Eur Radiol. 2012 Apr;22(4):864-71. doi: 10.1007/s00330-011-2333-x. Epub 2011 Nov 23.
7
Oxaliplatin-mediated increase in spleen size as a biomarker for the development of hepatic sinusoidal injury.奥沙利铂介导的脾脏增大可作为肝窦损伤发展的生物标志物。
J Clin Oncol. 2010 May 20;28(15):2549-55. doi: 10.1200/JCO.2009.27.5701. Epub 2010 Apr 20.
8
Predicting high grade lesions of sinusoidal obstruction syndrome related to oxaliplatin-based chemotherapy for colorectal liver metastases: correlation with post-hepatectomy outcome.预测结直肠肝转移瘤患者接受奥沙利铂为基础的化疗后发生肝窦阻塞综合征高分级病变：与肝切除术后结局的相关性。
Ann Surg. 2010 Mar;251(3):454-60. doi: 10.1097/SLA.0b013e3181c79403.
9
Sinusoidal obstructive syndrome diagnosed with superparamagnetic iron oxide-enhanced magnetic resonance imaging in patients with chemotherapy-treated colorectal liver metastases.经超顺磁性氧化铁增强磁共振成像诊断化疗治疗的结直肠癌肝转移患者的窦性阻塞综合征
J Clin Oncol. 2008 Sep 10;26(26):4304-10. doi: 10.1200/JCO.2008.16.1893.