Anneroth G, Hansen L S, Silverman S
J Oral Pathol. 1986 Mar;15(3):162-8. doi: 10.1111/j.1600-0714.1986.tb00599.x.
In a retrospective histological and clinical study, a multifactorial grading system was used for histological classification and grading of malignancy in 51 cases of squamous cell carcinoma of the tongue and floor of mouth. The results indicated that the use of such a multifactorial grading system, consisting of 7 morphological parameters, including an evaluation of both the tumor cell population itself and the tumor-host relationship, can serve as an important supplement to clinical judgement in determining the outcome of the oral tumor.
在一项回顾性组织学和临床研究中，采用多因素分级系统对51例舌癌和口底癌进行组织学分类和恶性程度分级。结果表明，这种由7个形态学参数组成的多因素分级系统，包括对肿瘤细胞群体本身以及肿瘤与宿主关系的评估，可作为临床判断口腔肿瘤预后的重要补充。
