Alizadeh Leila, Shakeri-Darzekonani Mahdieh, Sadrazar Amin, Nouri-Vaskeh Masoud, Basirjafari Sedigheh
Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Arch Acad Emerg Med. 2019 Jan 3;7(1):e12. eCollection 2019 Winter.
Peptic ulcer disease is a common gastrointestinal disorder, the prevalence of which has reduced in recent years due to effective new treatments. Peptic ulcer perforation is an emergent life-threatening condition that causes pneumoperitoneum and septic shock. It often requires surgical procedures. We describe two cases of peptic ulcer perforation with only mild discomfort on the epigastric region since several months before. The patients were treated with a high dose proton pump inhibitor and conservative treatment without surgical procedures. Weekly follow up of the cases showed that the clinical condition of patients remained stable without any new signs and symptoms. This report shows that noninvasive treatment alone can be effective in some cases with mild symptoms.
消化性溃疡病是一种常见的胃肠道疾病，由于有效的新治疗方法，其近年来的患病率有所下降。消化性溃疡穿孔是一种危及生命的紧急情况，可导致气腹和感染性休克。它通常需要外科手术。我们描述了两例自数月前以来仅在上腹部区域有轻度不适的消化性溃疡穿孔病例。患者接受了高剂量质子泵抑制剂治疗和保守治疗，未进行外科手术。对这些病例的每周随访显示，患者的临床状况保持稳定，没有任何新的体征和症状。本报告表明，在某些症状较轻的病例中，仅采用非侵入性治疗可能有效。
