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[良性前列腺增生的外科治疗——切除术、汽化术还是剜除术?]

[Surgical treatment of benign prostatic hyperplasia-resection, vaporization or enucleation?].

作者信息

Rieken M, Herrmann T R W, Füllhase C

机构信息

alta uro AG, Centralbahnplatz 6, 4051, Basel, Schweiz.

Universität Basel, Basel, Schweiz.

出版信息

Urologe A. 2019 Mar;58(3):263-270. doi: 10.1007/s00120-019-0891-8.

Abstract

BACKGROUND

Benign prostatic hyperplasia (BPH) is the most common condition affecting the male lower urinary tract. Besides transurethral resection of the prostate (TURP), vaporization of the prostate and endoscopic enucleation of the prostate are available.

OBJECTIVES

To provide an overview of the current status of surgical therapies for BPH.

MATERIALS AND METHODS

Narrative review of the literature on the surgical treatment of BPH.

RESULTS

Besides TURP, which still can be regarded as the reference technique for surgical treatment of BPH in men with a prostate volume <80 cc, greenlight laser vaporization of the prostate (GLV) and endoscopic enucleation of the prostate (EEP) are established and evidence-based alternatives. A multitude of prospective randomized trials could show comparable functional outcomes of GLV or EEP in comparison to TURP. Based on lower comorbidity and comparable outcomes, bipolar TURP rather than monopolar TURP should be regarded as the surgical reference technique. In patients with ongoing oral anticoagulation of thrombocyte aggregation inhibition, GLV provides high intra- und postoperative safety. Endoscopic enucleation of the prostate is the only transurethral surgical method which provides high level evidence concerning safety and efficacy in patients with prostates >80 cc.

CONCLUSIONS

Choice of surgical treatment of BPH should be individualized and based on prostate size, comorbidities and surgical experience.

摘要

背景

良性前列腺增生(BPH)是影响男性下尿路的最常见病症。除经尿道前列腺切除术(TURP)外,还有前列腺汽化术和前列腺内镜剜除术。

目的

概述BPH手术治疗的现状。

材料与方法

对BPH手术治疗的文献进行叙述性综述。

结果

除TURP(对于前列腺体积<80 cc的男性,TURP仍可被视为BPH手术治疗的参考技术)外,绿激光前列腺汽化术(GLV)和前列腺内镜剜除术(EEP)是已确立的、有循证依据的替代方法。大量前瞻性随机试验表明,与TURP相比,GLV或EEP的功能结局相当。基于较低的合并症发生率和相当的结局,双极TURP而非单极TURP应被视为手术参考技术。对于正在接受口服抗凝或血小板聚集抑制治疗的患者,GLV在术中及术后具有较高的安全性。前列腺内镜剜除术是唯一一种能为前列腺体积>80 cc的患者的安全性和有效性提供高级别证据的经尿道手术方法。

结论

BPH手术治疗的选择应个体化,并基于前列腺大小、合并症和手术经验。

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