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拓宽继发性头痛谱:非动脉瘤性蛛网膜下腔出血后低颅压。

Widening the spectrum of secondary headache: intracranial hypotension following a non-aneurysmal subarachnoid hemorrhage.

机构信息

Neurology Service and Stroke Unit, Department of Neuroscience, AO Brotzu, Cagliari, Italy.

Radiology Department, AO Brotzu, Cagliari, Italy.

出版信息

Neurol Sci. 2019 Oct;40(10):2179-2181. doi: 10.1007/s10072-019-03809-3. Epub 2019 Mar 7.

DOI:10.1007/s10072-019-03809-3
PMID:30847675
Abstract

BACKGROUND

Intracranial hypotension has been associated with a wide spectrum of neurological conditions including chronic non-aneurysmal and acute aneurysmal subarachnoid hemorrhage.

CASE

A 59-year-old man presented with a non-aneurysmal subarachnoid hemorrhage in a perimesencephalic pattern after a mild physical exertion. In the course of the disease, a magnetic resonance imaging of head and spine displayed intracranial hypotension that resolved spontaneously.

DISCUSSION

Long-standing intracranial hypotension has been reported as the cause of chronic subarachnoid hemorrhage and a single case of intracranial hypotension as the consequence of intracranial pressure fluctuations after acute aneurysmal subarachnoid hemorrhage has been described. This is the first description of intracranial hypotension caused by acute non-aneurysmal subarachnoid hemorrhage. We hypothesize that blood in the subarachnoid space could have determined a spine cerebrospinal fluid leak through intracranial pressure fluctuations or mechanical action, causing arachnoiditis and possibly a dural tear.

摘要

背景

颅内低血压与广泛的神经系统疾病相关,包括慢性非动脉瘤性和急性动脉瘤性蛛网膜下腔出血。

病例

一名 59 岁男性在轻度体力活动后出现中脑周围模式的非动脉瘤性蛛网膜下腔出血。在疾病过程中,头部和脊柱的磁共振成像显示颅内低血压,自发性缓解。

讨论

据报道,长期颅内低血压是慢性蛛网膜下腔出血的原因,而颅内压波动后急性动脉瘤性蛛网膜下腔出血导致颅内低血压的单一病例也有描述。这是颅内低血压由急性非动脉瘤性蛛网膜下腔出血引起的首例描述。我们假设蛛网膜下腔中的血液可能通过颅内压波动或机械作用导致脊柱脑脊液漏,引起蛛网膜炎并可能导致硬脑膜撕裂。

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引用本文的文献

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PLoS One. 2022 Sep 30;17(9):e0274634. doi: 10.1371/journal.pone.0274634. eCollection 2022.

本文引用的文献

1
A classification system of spontaneous spinal CSF leaks.自发性脊柱脑脊液漏的分类系统。
Neurology. 2016 Aug 16;87(7):673-9. doi: 10.1212/WNL.0000000000002986. Epub 2016 Jul 20.
2
Diffuse non-aneurysmal SAH in spontaneous intracranial hypotension: Sequela of ventral CSF leak?自发性颅内低压中的弥漫性非动脉瘤性蛛网膜下腔出血:腹侧脑脊液漏的后遗症?
Cephalalgia. 2016 May;36(6):589-92. doi: 10.1177/0333102415604473. Epub 2015 Sep 7.
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Superficial siderosis following spontaneous intracranial hypotension.自发性颅内低压后的表面铁沉积症
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Spontaneous CSF leaks: low CSF volume syndromes.自发性脑脊液漏:低脑脊液容量综合征。
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Intracranial hypotension in the setting of concurrent perineural cyst rupture and subarachnoid hemorrhage.颅内低压症合并神经周围囊肿破裂和蛛网膜下腔出血。
J Clin Neurosci. 2014 Jun;21(6):1063-5. doi: 10.1016/j.jocn.2013.10.011. Epub 2013 Oct 30.
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Chronic cerebellar hemorrhage in spontaneous intracranial hypotension: association with ventral spinal cerebrospinal fluid leaks: clinical article.自发性颅内低血压性慢性小脑血肿:与脊髓腹侧脑脊液漏相关:临床文章。
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Perimesencephalic subarachnoid hemorrhage: incidence, risk factors, and outcome.中脑周围蛛网膜下腔出血:发病率、危险因素及预后
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Intracranial aneurysms.颅内动脉瘤
N Engl J Med. 1997 Jan 2;336(1):28-40. doi: 10.1056/NEJM199701023360106.