University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Department of Pediatric Oncology/Hematology, Groningen, the Netherlands.
Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
Pediatr Blood Cancer. 2019 Jun;66(6):e27698. doi: 10.1002/pbc.27698. Epub 2019 Mar 7.
Although pain is one of the most prevalent and bothersome symptoms children with cancer experience, evidence-based guidance regarding assessment and management is lacking. With 44 international, multidisciplinary healthcare professionals and nine patient representatives, we aimed to develop a clinical practice guideline (following GRADE methodology), addressing assessment and pharmacological, psychological, and physical management of tumor-, treatment-, and procedure-related pain in children with cancer. In this paper, we present our thorough methodology for this development, including the challenges we faced and how we approached these. This lays the foundation for our clinical practice guideline, for which there is a high clinical demand.
尽管疼痛是儿童癌症患者最常见和最困扰的症状之一，但缺乏基于证据的评估和管理指导。我们召集了 44 名国际多学科医疗保健专业人员和 9 名患者代表，旨在制定一个临床实践指南（遵循 GRADE 方法），解决儿童癌症肿瘤、治疗和程序相关疼痛的评估以及药物、心理和物理管理问题。在本文中，我们介绍了我们在这一开发过程中所采用的全面方法，包括我们所面临的挑战以及我们如何处理这些挑战。这为我们的临床实践指南奠定了基础，该指南具有很高的临床需求。
