Kono M, O'Hara K, Ohmiya K, Iida H, Kibayashi C, Kasahara K
Jpn J Antibiot. 1986 Jan;39(1):247-9.
Antibacterial activity of (+)-negamycin (NGM) prepared by a new method was investigated for some bacteria. The results demonstrated that this antibacterial activity of synthesized NGM was almost the same as compared to that of naturally obtained NGM, and was also effective to Pseudomonas aeruginosa harboring multiple drug resistant plasmid kR102.
采用新方法制备的(+)-负霉素(NGM)对某些细菌的抗菌活性进行了研究。结果表明,合成的NGM的这种抗菌活性与天然获得的NGM相比几乎相同,并且对携带多重耐药质粒kR102的铜绿假单胞菌也有效。