Department of Biology, New York University, NY 10003, USA.
Department of Biology, New York University, NY 10003, USA.
Curr Opin Neurobiol. 2019 Jun;56:153-159. doi: 10.1016/j.conb.2019.01.024. Epub 2019 Mar 5.
Precise formation of neuronal circuits requires the coordinated development of the different components of the circuit. Here, we review examples of coordination at multiples scales of development in one of the best-studied systems for neural patterning and circuit assembly, the Drosophila visual system, from coordination of gene expression in photoreceptors to the coordinated patterning of the different neuropiles of the optic lobe.
精确的神经元回路形成需要回路的不同组成部分的协调发育。在这里,我们回顾了在神经模式形成和回路组装的最佳研究系统之一——果蝇视觉系统中,多个发育尺度上的协调的例子,从光感受器中的基因表达协调到视神经叶的不同神经叶的协调模式形成。