Archer L N, Evans D H, Paton J Y, Levene M I
Pediatr Res. 1986 Mar;20(3):218-21. doi: 10.1203/00006450-198603000-00004.
Eleven normal term infants undergoing respiratory assessment involving rebreathing to produce progressive hypercapnia were studied by Doppler ultrasound examination of an anterior cerebral artery during the procedure. A linear increase in end tidal carbon dioxide concentration from 4.5% to a maximum of 8.5% was documented during a period of 4-5 min rebreathing. A corresponding elevation of transcutaneous carbon dioxide tension was shown in the two infants monitored in this way. In all cases the Pourcelot index fell with rising end tidal carbon dioxide concentration. This fall in Pourcelot index was due to an increase in the diastolic frequency of the Doppler waveform. These results are consistent with the view that Pourcelot index correlates with cerebral vascular resistance distal to the site of recording.
对11名足月正常婴儿进行了呼吸评估，评估过程中通过重复呼吸产生渐进性高碳酸血症，并在此过程中对大脑前动脉进行多普勒超声检查。在4 - 5分钟的重复呼吸期间，呼气末二氧化碳浓度从4.5%呈线性增加，最高达到8.5%。以这种方式监测的两名婴儿显示经皮二氧化碳张力相应升高。在所有病例中，随着呼气末二氧化碳浓度升高，普尔塞洛指数下降。普尔塞洛指数的下降是由于多普勒波形舒张期频率增加所致。这些结果与以下观点一致，即普尔塞洛指数与记录部位远端的脑血管阻力相关。
