University of Washington, United States.
University of Washington, United States.
Int J Drug Policy. 2019 May;67:24-33. doi: 10.1016/j.drugpo.2019.01.002. Epub 2019 Mar 6.
People experiencing homelessness are disproportionately affected by alcohol use disorder (AUD). Abstinence-based treatment, however, does not optimally engage or treat this population. Thus, harm reduction treatment for alcohol (HaRT-A) was developed together with people with lived experience of homelessness and AUD and community-based agencies that serve them. HaRT-A is a compassionate and pragmatic approach that aims to help people reduce alcohol-related harm and improve quality of life (QoL) without requiring abstinence or use reduction. A three-month, two-arm randomized controlled trial was conducted to test the initial efficacy of HaRT-A compared to a services-as-usual control condition.
People experiencing homelessness and AUD (N = 168; 24% women) were recruited in community-based clinical and social services settings. Self-reported alcohol use, alcohol-related harm, motivation, and QoL as well as urinary ethyl glucuronide were assessed over a 3-month follow-up. Participants were randomized to receive HaRT-A or services as usual. Over four sessions, HaRT-A interventionists delivered three components: a) collaborative tracking of participant-preferred alcohol metrics, b) elicitation of harm-reduction and QoL goals, and c) discussion of safer-drinking strategies.
Compared to control participants, HaRT-A participants reported significantly greater increases in confidence to engage in harm reduction and decreases in peak alcohol use, alcohol-related harm, AUD symptoms, and positive urinary ethyl glucuronide tests (ps < .05). Findings were inconclusive regarding group differences on QoL (ps > .12).
A low-barrier, low-intensity, patient-driven, harm-reduction approach has at least short-term efficacy in improving AUD outcomes in this population. Future studies are needed to establish its longer-term efficacy.
无家可归者受到酒精使用障碍(AUD)的影响不成比例。然而,基于禁欲的治疗方法并不能使这一人群得到最佳的参与或治疗。因此,开发了针对酒精的减少伤害治疗(HaRT-A),该方法是与有酗酒和 AUD 经历的人和为他们服务的社区机构共同开发的。HaRT-A 是一种富有同情心和务实的方法,旨在帮助人们减少与酒精相关的伤害,提高生活质量(QoL),而无需禁欲或减少使用。进行了一项为期三个月的、两臂随机对照试验,以测试 HaRT-A 与常规服务对照条件相比的初始疗效。
在社区临床和社会服务环境中招募了无家可归且患有 AUD(N=168;24%为女性)的个体。在 3 个月的随访中,评估了自我报告的饮酒量、与饮酒相关的伤害、动机和 QoL 以及尿液乙基葡萄糖醛酸苷。参与者被随机分配接受 HaRT-A 或常规服务。在四次会议中,HaRT-A 干预者提供了三个部分:a)共同跟踪参与者首选的酒精指标,b)引出减少伤害和 QoL 目标,以及 c)讨论更安全的饮酒策略。
与对照组参与者相比,HaRT-A 参与者报告在参与减少伤害的信心方面有显著增加,在峰值饮酒量、与饮酒相关的伤害、AUD 症状和阳性尿液乙基葡萄糖醛酸苷检测方面有显著减少(p<0.05)。关于 QoL 的组间差异,结果不确定(p>0.12)。
一种低门槛、低强度、以患者为驱动、以减少伤害为重点的方法至少在短期内对改善该人群的 AUD 结局具有疗效。需要进一步的研究来确定其长期疗效。