University of North Carolina at Chapel Hill, Davie Hall, Campus Box 3270, Chapel Hill, NC, 27599, United States; Massachusetts General Hospital / Harvard Medical School, 185 Cambridge St, Boston, MA, 02114, United States.
University of North Carolina at Chapel Hill, Davie Hall, Campus Box 3270, Chapel Hill, NC, 27599, United States.
J Behav Ther Exp Psychiatry. 2019 Sep;64:54-63. doi: 10.1016/j.jbtep.2019.02.008. Epub 2019 Feb 26.
Although research suggests that introducing varying levels of fear during exposure enhances outcomes for some anxiety-related problems, this has not been examined in the context of obsessions. The current preliminary study tested the hypothesis that introducing variability in exposure intensity would improve long-term outcomes relative to traditional gradual (hierarchical) exposure METHODS: Adults (N = 40) with a moderately distressing unacceptable obsessional thought were randomly assigned in parallel to four twice-weekly sessions of: (a) gradual exposure (EXP-G; n = 19) emphasizing hierarchical exposure completion, or (b) variable exposure (EXP-V; n = 21) emphasizing variability in exposure intensity RESULTS: There were no significant differences in pre to post changes between groups using self-report, interview, or behavioral outcomes (as evaluated by an independent assessor blind to treatment condition). Group comparisons at 3-month follow-up did not reach statistical significance but were moderate in magnitude. Specifically, as measured by clinical interview (the Yale-Brown Obsessive-Compulsive Scale; primary outcome) and self-report, individuals in the EXP-G group maintained gains at 3-month follow-up, while the EXP-V group continued to improve. Treatment expectancies and satisfaction were comparable for both groups. Five participants withdrew from the EXP-G condition, and none withdrew from the EXP-V condition. In contrast to previous studies, variability in subjective and physiological fear during exposure did not predict outcomes LIMITATIONS: The study employed an analogue sample with moderate unacceptable obsessions, and results should be replicated in clinical samples CONCLUSIONS: Variable exposure warrants future study to understand the mechanisms, moderators, and implications of this novel approach.
虽然研究表明,在暴露治疗中引入不同程度的恐惧可以提高某些与焦虑相关问题的治疗效果,但这在强迫观念的背景下尚未得到检验。本初步研究检验了以下假设,即在暴露强度上引入可变性会改善长期治疗效果,优于传统的逐渐(层级)暴露治疗方法。研究纳入了 40 名具有中度困扰的不可接受的强迫观念的成年人,他们被随机分为两组,分别接受每周两次共四次的治疗:(a)逐渐暴露治疗(EXP-G;n=19),强调层级暴露完成;或(b)变化暴露治疗(EXP-V;n=21),强调暴露强度的可变性。研究结果显示,两组在自我报告、访谈或行为结果(由不了解治疗条件的独立评估者评估)方面,治疗前后的变化没有显著差异。在 3 个月的随访中,组间比较没有达到统计学意义,但具有中等程度的差异。具体来说,根据临床访谈(耶鲁-布朗强迫量表;主要结局)和自我报告评估,EXP-G 组的个体在 3 个月的随访中保持了治疗效果的提高,而 EXP-V 组则继续改善。两组的治疗预期和满意度相当。有 5 名参与者退出了 EXP-G 组,没有参与者退出 EXP-V 组。与之前的研究不同,暴露过程中主观和生理恐惧的可变性并不能预测治疗效果。研究的局限性在于,研究采用了中度不可接受的强迫观念的模拟样本,结果应在临床样本中得到复制。结论:变化暴露值得进一步研究,以了解这种新方法的机制、调节因素和影响。