Greaves W L, Rodrigues L M, Anderson B, Biddle J, Wittington W L
South Med J. 1986 Apr;79(4):420-3. doi: 10.1097/00007611-198604000-00008.
Previous outbreaks of penicillinase-producing gonococcal infection in the United States have generally been attributed to importation of Southeast Asian strains. During July 1982 through July 1983, 110 cases of gonorrhea caused by penicillinase-producing strains were reported in metropolitan Atlanta, Georgia. Among the 53 infected women, 14 (26%) had pelvic inflammatory disease (PID). Compared to other infected women, those with PID experienced a greater delay from the time of last sexual exposure (19.1 vs 8.1 days) to receipt of appropriate antibiotic therapy (P less than .01). At least 22 prostitutes were involved in the outbreak. Sixteen (76%) of 21 isolates tested were serogroup 1A; 15 required arginine and proline for growth; and 17 (81%) possessed a 3.2 megadalton plasmid. Our data suggest that this outbreak was associated with both African and Southeast Asian strains.
美国以往产青霉素酶淋病奈瑟菌感染的暴发通常归因于东南亚菌株的输入。在1982年7月至1983年7月期间，佐治亚州亚特兰大大都市地区报告了110例由产青霉素酶菌株引起的淋病病例。在53名受感染女性中，14名（26%）患有盆腔炎（PID）。与其他受感染女性相比，患有PID的女性从最后一次性接触（19.1天对8.1天）到接受适当抗生素治疗的延迟时间更长（P<0.01）。此次暴发至少涉及22名妓女。检测的21株菌株中有16株（76%）属于血清群1A；15株生长需要精氨酸和脯氨酸；17株（81%）拥有一个3.2兆道尔顿的质粒。我们的数据表明，此次暴发与非洲菌株和东南亚菌株均有关。
