Metabolic Pole and Nephrology Department, Jacques Lacarin Vichy General Hospital, Vichy, France
Metabolic Pole and Nephrology Department, Jacques Lacarin Vichy General Hospital, Vichy, France.
Perit Dial Int. 2019 Sep-Oct;39(5):399-404. doi: 10.3747/pdi.2018.00169. Epub 2019 Mar 9.
Constipation in peritoneal dialysis (PD) is an infrequent but potentially serious condition affecting the mechanical properties of dialysis techniques and predisposing to bacterial intestinal translocation and eventual enteric peritonitis. Despite the importance of the problem, published literature is scarce, consisting mostly of uncontrolled single-center trials. This inconsistency may be attributed to the large number of clinical, radiological, and endoscopic tools that have been used in the studies with a lack of generally accepted core primary outcomes.The current narrative review discusses the pathophysiological associations between chronic kidney disease, PD, and constipation with related complication.
在腹膜透析（PD）中，便秘是一种不常见但潜在严重的情况，会影响透析技术的机械性能，并导致细菌肠道易位和最终发生肠源性腹膜炎。尽管这个问题很重要，但已发表的文献很少，主要是单中心的非对照试验。这种不一致性可能归因于研究中使用了大量的临床、放射学和内镜工具，而缺乏普遍接受的核心主要结局。本文综述讨论了慢性肾脏病、PD 和便秘之间的病理生理关联及其相关并发症。
