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The new kid on the block: suicide gene therapy to modulate cancer immunosurveillance for children with high-risk malignant brain tumors.

作者信息

Sait Sameer F, Karajannis Matthias A

机构信息

Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.

出版信息

Neuro Oncol. 2019 Mar 18;21(4):419-420. doi: 10.1093/neuonc/noz026.

DOI:10.1093/neuonc/noz026
PMID:30852609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6422432/
Abstract
摘要

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本文引用的文献

1
Phase I study of gene-mediated cytotoxic immunotherapy with AdV-tk as adjuvant to surgery and radiation for pediatric malignant glioma and recurrent ependymoma.以 AdV-tk 为辅助手段的基因介导细胞毒性免疫治疗联合手术和放疗治疗小儿恶性胶质瘤和复发性室管膜瘤的 I 期研究。
Neuro Oncol. 2019 Mar 18;21(4):537-546. doi: 10.1093/neuonc/noy202.
2
Immunotherapy of Primary Brain Tumors: Facts and Hopes.原发性脑肿瘤的免疫治疗:现状与展望。
Clin Cancer Res. 2018 Nov 1;24(21):5198-5205. doi: 10.1158/1078-0432.CCR-17-2769. Epub 2018 Jun 5.
3
Pediatric high-grade glioma: biologically and clinically in need of new thinking.小儿高级别胶质瘤:在生物学和临床上都需要新思维。
Neuro Oncol. 2017 Feb 1;19(2):153-161. doi: 10.1093/neuonc/now101.
4
Phase II multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma.基因介导的细胞毒性免疫疗法作为新诊断恶性胶质瘤手术切除辅助治疗的II期多中心研究。
Neuro Oncol. 2016 Aug;18(8):1137-45. doi: 10.1093/neuonc/now002. Epub 2016 Feb 2.
5
Cytotoxic immunotherapy strategies for cancer: mechanisms and clinical development.癌症的细胞毒性免疫治疗策略:机制与临床开发。
J Cell Biochem. 2011 Aug;112(8):1969-77. doi: 10.1002/jcb.23126.
6
Prostate cancer gene therapy: herpes simplex virus thymidine kinase gene transduction followed by ganciclovir in mouse and human prostate cancer models.前列腺癌基因治疗:在小鼠和人类前列腺癌模型中,单纯疱疹病毒胸苷激酶基因转导后给予更昔洛韦。
Hum Gene Ther. 1996 Mar 1;7(4):515-23. doi: 10.1089/hum.1996.7.4-515.
7
The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.“旁观者效应”:当一部分肿瘤组织进行基因改造时肿瘤发生消退。
Cancer Res. 1993 Nov 1;53(21):5274-83.