Clinical Microbiology Laboratory, The Baruch Padeh Medical Center, Poriya, Tiberias, Israel.
The Otolaryngology, Head and Neck Surgery Unit, The Baruch Padeh Medical Center, Poriya, Tiberias, Israel.
Eur J Clin Microbiol Infect Dis. 2019 Jun;38(6):1179-1185. doi: 10.1007/s10096-019-03527-w. Epub 2019 Mar 9.
We compared the performance of two rapid antigen tests-QuikRead go® Strep A test (Orion Diagnostica, Espoo, Finland) and BD Veritor™ system (Becton, Dickinson and Company, Sparks, MD) with throat culture. Our aim was to evaluate each assay's performance and agreement compared to throat culture in order to choose one of the assays as a point-of-care test in the emergency room. One hundred throat samples were collected in triplicates from patients with suspected pharyngitis admitted to the emergency room. One throat swab was seeded for a throat culture. The other two throat swabs from each patient were analyzed at the emergency room by the QuikRead go® Strep A test, and by the BD Veritor™ system, according to each manufacturer's instructions. Agreement level between BD Veritor™ test and throat culture was 79%; sensitivity and specificity of this test were 80% and 78.7%, respectively. QuikRead go® Strep A test had an agreement level of 75% with throat culture; sensitivity and specificity of this test were 80% and 73.3%, respectively. Both tests have a good diagnostic performance. Other characteristics such as costs, size of instrument, and ease of implementation should be taken into consideration when choosing a point-of-care test.
我们比较了两种快速抗原检测方法——QuikRead go® Strep A 检测（Orion Diagnostica，埃斯波，芬兰）和 BD Veritor™ 系统（Becton，Dickinson and Company，斯帕克斯，MD）与咽拭子培养的性能。我们的目的是评估每种检测方法与咽拭子培养的性能和一致性，以便选择其中一种检测方法作为急诊室的即时检测方法。从急诊室疑似咽炎的患者中采集了 100 份咽拭子样本，进行了三份重复。一份咽拭子用于咽拭子培养。每位患者的另外两份咽拭子分别按照制造商的说明，在急诊室用 QuikRead go® Strep A 检测和 BD Veritor™ 系统进行分析。BD Veritor™ 检测与咽拭子培养的一致性为 79%；该检测的敏感性和特异性分别为 80%和 78.7%。QuikRead go® Strep A 检测与咽拭子培养的一致性为 75%；该检测的敏感性和特异性分别为 80%和 73.3%。这两种检测方法都具有良好的诊断性能。在选择即时检测方法时，还应考虑其他特征，如成本、仪器大小和实施的简便性。
