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Abnormal Brain Structure and Function in First-Episode Childhood- and Adolescence-Onset Schizophrenia: Association with Clinical Symptoms.首发儿童及青少年期精神分裂症患者的脑结构与功能异常：与临床症状的关联
Neurosci Bull. 2019 Jun;35(3):522-526. doi: 10.1007/s12264-019-00359-8. Epub 2019 Mar 9.
2
Structural neural networks subserving oculomotor function in first-episode schizophrenia.首发精神分裂症中维持眼球运动功能的结构性神经网络。
Biol Psychiatry. 2004 Nov 1;56(9):620-7. doi: 10.1016/j.biopsych.2004.08.017.
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Association of cerebral deficits with clinical symptoms in antipsychotic-naive first-episode schizophrenia: an optimized voxel-based morphometry and resting state functional connectivity study.首发未使用抗精神病药物的精神分裂症患者脑功能缺陷与临床症状的关联：一项基于体素的形态学优化及静息态功能连接研究
Am J Psychiatry. 2009 Feb;166(2):196-205. doi: 10.1176/appi.ajp.2008.08020183. Epub 2008 Nov 3.
4
Connecting brain structure and function in schizophrenia.连接精神分裂症中的脑结构与功能。
Am J Psychiatry. 2009 Feb;166(2):134-6. doi: 10.1176/appi.ajp.2008.08111685.
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Psychol Med. 2008 Jun;38(6):877-85. doi: 10.1017/S0033291707001808. Epub 2007 Oct 22.
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White matter abnormalities and brain activation in schizophrenia: a combined DTI and fMRI study.精神分裂症中的白质异常与脑激活：一项弥散张量成像（DTI）与功能磁共振成像（fMRI）的联合研究
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Magnetic Resonance Imaging-Guided and Navigated Individualized Repetitive Transcranial Magnetic Stimulation for Cognitive Impairment in Schizophrenia.磁共振成像引导和导航的个体化重复经颅磁刺激治疗精神分裂症认知障碍
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本文引用的文献

1
Abnormal long- and short-range functional connectivity in adolescent-onset schizophrenia patients: A resting-state fMRI study.青少年发病精神分裂症患者异常的长程和短程功能连接：一项静息态 fMRI 研究。
Prog Neuropsychopharmacol Biol Psychiatry. 2018 Feb 2;81:445-451. doi: 10.1016/j.pnpbp.2017.08.012. Epub 2017 Aug 17.
2
Abnormal regional homogeneity as a potential imaging biomarker for adolescent-onset schizophrenia: A resting-state fMRI study and support vector machine analysis.异常局部一致性作为青少年发病精神分裂症的潜在影像生物标志物：一项静息态 fMRI 研究和支持向量机分析。
Schizophr Res. 2018 Feb;192:179-184. doi: 10.1016/j.schres.2017.05.038. Epub 2017 Jun 3.
3
Whole brain volume changes and its correlation with clinical symptom severity in patients with schizophrenia: A DARTEL-based VBM study.精神分裂症患者全脑体积变化及其与临床症状严重程度的相关性：一项基于DARTEL的体素形态学研究
PLoS One. 2017 May 17;12(5):e0177251. doi: 10.1371/journal.pone.0177251. eCollection 2017.
4
Abnormal neural activity as a potential biomarker for drug-naive first-episode adolescent-onset schizophrenia with coherence regional homogeneity and support vector machine analyses.异常神经活动作为一种潜在的生物标志物，用于对未经药物治疗的首发青少年起病精神分裂症进行相干区域同质性和支持向量机分析。
Schizophr Res. 2018 Feb;192:408-415. doi: 10.1016/j.schres.2017.04.028. Epub 2017 May 2.
5
Abnormally increased and incoherent resting-state activity is shared between patients with schizophrenia and their unaffected siblings.精神分裂症患者及其未患病的兄弟姐妹之间存在静息状态活动异常增加且不协调的情况。
Schizophr Res. 2016 Mar;171(1-3):158-65. doi: 10.1016/j.schres.2016.01.022. Epub 2016 Jan 21.
6
White matter volume change and its correlation with symptom severity in patients with schizophrenia: a VBM-DARTEL study.精神分裂症患者白质体积变化及其与症状严重程度的相关性：一项基于体素的形态学分析- DARTEL研究
Neuroreport. 2015 Dec 16;26(18):1095-100. doi: 10.1097/WNR.0000000000000471.
7
Progressive brain changes in children and adolescents with early-onset psychosis: A meta-analysis of longitudinal MRI studies.早发性精神病儿童和青少年的渐进性脑变化：纵向MRI研究的荟萃分析
Schizophr Res. 2016 Jun;173(3):132-139. doi: 10.1016/j.schres.2014.12.022. Epub 2014 Dec 31.
8
Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia.脑白质异常及其与精神分裂症阴性症状而非阳性症状的相关性。
Psychiatry Res. 2014 Apr 30;222(1-2):52-9. doi: 10.1016/j.pscychresns.2014.02.007. Epub 2014 Feb 19.
9
A comparison of neuroimaging findings in childhood onset schizophrenia and autism spectrum disorder: a review of the literature.儿童期起病的精神分裂症与自闭症谱系障碍的神经影像学研究结果比较：文献综述
Front Psychiatry. 2013 Dec 20;4:175. doi: 10.3389/fpsyt.2013.00175.
10
Association of white matter deficits with clinical symptoms in antipsychotic-naive first-episode schizophrenia: an optimized VBM study using 3T.首发未服用抗精神病药物的精神分裂症患者白质缺陷与临床症状的关联：一项使用3T的优化体素形态学研究
MAGMA. 2014 Aug;27(4):283-90. doi: 10.1007/s10334-013-0411-6. Epub 2013 Oct 8.

Abnormal Brain Structure and Function in First-Episode Childhood- and Adolescence-Onset Schizophrenia: Association with Clinical Symptoms.

作者信息

Xia Yanhong, Lv Dan, Liang Yinghui, Zhang Haisan, Pei Keyang, Shao Rongrong, Li Yali, Zhang Yan, Li Yuling, Guo Jinghua, Lv Luxian, Guo Suqin

机构信息

Department of Child and Adolescent Psychiatry, Henan Mental Hospital, The Second Affiliated Hospital of Xinxaing Medical University, Xinxiang, 453002, China.

Institute of Mental health, School of Psychiatry, Qiqihaer Medical University, Qiqihar, 161006, China.

出版信息

Neurosci Bull. 2019 Jun;35(3):522-526. doi: 10.1007/s12264-019-00359-8. Epub 2019 Mar 9.

DOI:10.1007/s12264-019-00359-8
PMID:30852802
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6527725/
Abstract
摘要