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木尘纵向健康研究综述:对职业接触限值的启示

A Review of Wood Dust Longitudinal Health Studies: Implications for an Occupational Limit Value.

作者信息

Holm Stewart E, Festa John L

机构信息

American Forest & Paper Association, Washington, DC, USA.

Consultant.

出版信息

Dose Response. 2019 Feb 28;17(1):1559325819827464. doi: 10.1177/1559325819827464. eCollection 2019 Jan-Mar.

Abstract

Numerous studies reporting on the health effects of wood dust have been published over many decades. For the clear majority of these studies, their use for setting a science-based occupational exposure level is problematic due generally to insufficient exposure measurement data, inadequate participant follow-up, and lack of control for confounding variables. However, there exists a robust data set from a large longitudinal lung function study that provides a scientifically sound basis for establishing an occupational limit of 5 mg/m inhalable wood dust. The choice of this data set and its application for this purpose are presented in this review.

摘要

几十年来,已经发表了许多关于木尘对健康影响的研究。对于这些研究中的绝大多数而言,由于暴露测量数据不足、参与者随访不充分以及缺乏对混杂变量的控制,将其用于设定基于科学的职业暴露水平存在问题。然而,一项大型纵向肺功能研究有一组可靠的数据集,为确定可吸入木尘的职业接触限值5毫克/立方米提供了科学依据。本综述介绍了该数据集的选择及其在此目的中的应用。

相似文献

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A Review of Wood Dust Longitudinal Health Studies: Implications for an Occupational Limit Value.木尘纵向健康研究综述:对职业接触限值的启示
Dose Response. 2019 Feb 28;17(1):1559325819827464. doi: 10.1177/1559325819827464. eCollection 2019 Jan-Mar.

本文引用的文献

1
Decreasing incidence of nasal adenocarcinoma in Wycombe woodworkers.怀科姆木工中鼻腔腺癌发病率的降低。
Laryngoscope. 2014 May;124(5):1078-82. doi: 10.1002/lary.24495. Epub 2013 Dec 10.
9
Nasal cancer in woodworkers in the furniture industry.家具行业木工中的鼻癌
Br Med J. 1968 Jun 8;2(5605):587-96. doi: 10.1136/bmj.2.5605.587.

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