Holm Stewart E, Festa John L
American Forest & Paper Association, Washington, DC, USA.
Consultant.
Dose Response. 2019 Feb 28;17(1):1559325819827464. doi: 10.1177/1559325819827464. eCollection 2019 Jan-Mar.
Numerous studies reporting on the health effects of wood dust have been published over many decades. For the clear majority of these studies, their use for setting a science-based occupational exposure level is problematic due generally to insufficient exposure measurement data, inadequate participant follow-up, and lack of control for confounding variables. However, there exists a robust data set from a large longitudinal lung function study that provides a scientifically sound basis for establishing an occupational limit of 5 mg/m inhalable wood dust. The choice of this data set and its application for this purpose are presented in this review.
几十年来，已经发表了许多关于木尘对健康影响的研究。对于这些研究中的绝大多数而言，由于暴露测量数据不足、参与者随访不充分以及缺乏对混杂变量的控制，将其用于设定基于科学的职业暴露水平存在问题。然而，一项大型纵向肺功能研究有一组可靠的数据集，为确定可吸入木尘的职业接触限值5毫克/立方米提供了科学依据。本综述介绍了该数据集的选择及其在此目的中的应用。
