• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections.

作者信息

Agarwal Rachit, Johnson Christopher T, Imhoff Barry R, Donlan Rodney M, McCarty Nael A, García Andrés J

机构信息

Woodruff School of Mechanical Engineering , Georgia Institute of Technology, Atlanta, GA, USA.

Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, USA.

出版信息

Nat Biomed Eng. 2018 Nov;2(11):841-849. doi: 10.1038/s41551-018-0263-5. Epub 2018 Jul 16.

DOI:10.1038/s41551-018-0263-5
PMID:30854250
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6408147/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/3ecaa11c810c/nihms-975544-f0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/6c838e47ad3b/nihms-975544-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/38ca1124d3d4/nihms-975544-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/52542d230a3b/nihms-975544-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/5e260b0587e5/nihms-975544-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/4f2d488b9389/nihms-975544-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/20354e497e2c/nihms-975544-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/3ecaa11c810c/nihms-975544-f0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/6c838e47ad3b/nihms-975544-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/38ca1124d3d4/nihms-975544-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/52542d230a3b/nihms-975544-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/5e260b0587e5/nihms-975544-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/4f2d488b9389/nihms-975544-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/20354e497e2c/nihms-975544-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731f/6408147/3ecaa11c810c/nihms-975544-f0007.jpg

相似文献

1
Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections.吸入载有噬菌体的聚合物微粒可改善急性肺部感染。
Nat Biomed Eng. 2018 Nov;2(11):841-849. doi: 10.1038/s41551-018-0263-5. Epub 2018 Jul 16.
2
Influence of polymeric carrier on the disposition and retention of 20(R)-ginsenoside-rg3-loaded swellable microparticles in the lung.聚合物载体对 20(R)-人参皂苷-rg3 载胀性微球在肺部的分布和滞留的影响。
Drug Deliv Transl Res. 2018 Feb;8(1):252-265. doi: 10.1007/s13346-017-0456-6.
3
Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery.用于肺部给药的低密度载阿奇霉素聚己内酯微粒的研制。
Drug Dev Ind Pharm. 2016 May;42(5):776-787. doi: 10.3109/03639045.2015.1075032. Epub 2015 Aug 12.
4
Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery.用于肺部给药的低密度载阿奇霉素聚己内酯微粒的研制。
Drug Dev Ind Pharm. 2016;42(5):776-87. doi: 10.3109/03639045.2015.1075032. Epub 2015 Aug 12.
5
Recombinant Filamentous Bacteriophages Encapsulated in Biodegradable Polymeric Microparticles for Stimulation of Innate and Adaptive Immune Responses.封装于可生物降解聚合物微粒中的重组丝状噬菌体,用于刺激天然免疫和适应性免疫反应。
Microorganisms. 2020 Apr 29;8(5):650. doi: 10.3390/microorganisms8050650.
6
PHEA-graft-polybutylmethacrylate copolymer microparticles for delivery of hydrophobic drugs.载有疏水性药物的 PHEA-接枝-聚丁基甲基丙烯酸酯共聚物微粒。
Int J Pharm. 2012 Aug 20;433(1-2):16-24. doi: 10.1016/j.ijpharm.2012.04.052. Epub 2012 Apr 27.
7
Budesonide nanocrystal-loaded hyaluronic acid microparticles for inhalation: In vitro and in vivo evaluation.载布地奈德纳米晶的透明质酸微球吸入剂:体外与体内评价。
Carbohydr Polym. 2018 Feb 1;181:1143-1152. doi: 10.1016/j.carbpol.2017.11.018. Epub 2017 Nov 4.
8
Improvement of the antibacterial activity of daptomycin-loaded polymeric microparticles by Eudragit RL 100: an assessment by isothermal microcalorimetry.载多黏菌素 B 聚合物微球的抗菌活性的改善:等温微量热法评估。
Int J Pharm. 2015 May 15;485(1-2):171-82. doi: 10.1016/j.ijpharm.2015.03.016. Epub 2015 Mar 12.
9
Preparation of budesonide-loaded porous PLGA microparticles and their therapeutic efficacy in a murine asthma model.载布地奈德多孔 PLGA 微球的制备及其在哮喘小鼠模型中的治疗效果。
J Control Release. 2011 Feb 28;150(1):56-62. doi: 10.1016/j.jconrel.2010.11.001. Epub 2010 Nov 9.
10
Preparation and Characterization of Doripenem-Loaded Microparticles for Pulmonary Delivery.载多利培南微球的制备及特性研究。
J Aerosol Med Pulm Drug Deliv. 2018 Dec;31(6):347-357. doi: 10.1089/jamp.2017.1378. Epub 2018 Jun 7.

引用本文的文献

1
Latest Advances in Inhalable Dry Powder Bacteriophage Therapy for Pulmonary Infections.吸入性干粉噬菌体治疗肺部感染的最新进展
Pharmaceutics. 2025 Aug 20;17(8):1077. doi: 10.3390/pharmaceutics17081077.
2
Inhalable nanoparticle-based delivery systems for the treatment of pulmonary infections: and barrier-overcoming strategies.用于治疗肺部感染的基于可吸入纳米颗粒的递送系统及克服屏障的策略。
Drug Deliv. 2025 Dec;32(1):2544683. doi: 10.1080/10717544.2025.2544683. Epub 2025 Aug 11.
3
Inhaled predatory bacteria-loaded large porous microspheres to eradicate drug-resistant from the lung.

本文引用的文献

1
Bacteriophage-based therapy in cystic fibrosis-associated Pseudomonas aeruginosa infections: rationale and current status.基于噬菌体的疗法在囊性纤维化相关铜绿假单胞菌感染中的应用:理论依据与现状
Drug Des Devel Ther. 2015 Jul 16;9:3653-63. doi: 10.2147/DDDT.S53123. eCollection 2015.
2
The pathogenesis of ventilator-associated pneumonia: its relevance to developing effective strategies for prevention.呼吸机相关性肺炎的发病机制:其与制定有效预防策略的相关性。
Respir Care. 2005 Jun;50(6):725-39; discussion 739-41.
吸入载有捕食性细菌的大孔微球以清除肺部的耐药菌。
Mater Today Bio. 2025 Feb 8;31:101562. doi: 10.1016/j.mtbio.2025.101562. eCollection 2025 Apr.
4
Bacteriophage therapy for multidrug-resistant infections: current technologies and therapeutic approaches.用于多重耐药感染的噬菌体疗法:当前技术与治疗方法
J Clin Invest. 2025 Mar 3;135(5):e187996. doi: 10.1172/JCI187996.
5
R-pyocins as targeted antimicrobials against Pseudomonas aeruginosa.R型绿脓菌素作为针对铜绿假单胞菌的靶向抗菌剂。
NPJ Antimicrob Resist. 2025 Feb 28;3(1):17. doi: 10.1038/s44259-025-00088-1.
6
Hybrid Cell Membrane-Engineered Nanocarrier for Triple-Action Strategy to Address Pseudomonas aeruginosa Infection.用于应对铜绿假单胞菌感染的三作用策略的混合细胞膜工程纳米载体
Adv Sci (Weinh). 2025 Feb;12(6):e2411261. doi: 10.1002/advs.202411261. Epub 2024 Dec 25.
7
Metapopulation model of phage therapy of an acute lung infection.噬菌体治疗急性肺部感染的复合种群模型。
mSystems. 2024 Oct 22;9(10):e0017124. doi: 10.1128/msystems.00171-24. Epub 2024 Sep 4.
8
Bacteriophages and Their Clinical Applications.噬菌体及其临床应用。
Viruses. 2024 Jun 29;16(7):1051. doi: 10.3390/v16071051.
9
Using tea nanoclusters as β-lactamase inhibitors to cure multidrug-resistant bacterial pneumonia: A promising therapeutic strategy by Chinese materioherbology.利用茶纳米簇作为β-内酰胺酶抑制剂治疗多重耐药细菌性肺炎:中药的一种有前景的治疗策略。
Fundam Res. 2021 Nov 25;2(3):496-504. doi: 10.1016/j.fmre.2021.11.019. eCollection 2022 May.
10
Advances and optimization strategies in bacteriophage therapy for treating inflammatory bowel disease.噬菌体治疗炎症性肠病的研究进展及优化策略。
Front Immunol. 2024 May 8;15:1398652. doi: 10.3389/fimmu.2024.1398652. eCollection 2024.