Farahani Keyvan, Tata Darrell, Nordstrom Robert J
Cancer Imaging Program, National Cancer Institute of NIH, Bethesda, MD.
Tomography. 2019 Mar;5(1):1-6. doi: 10.18383/j.tom.2018.00045.
The Quantitative Imaging Network of the National Cancer Institute is in its 10th year of operation, and research teams within the network are developing and validating clinical decision support software tools to measure or predict the response of cancers to various therapies. As projects progress from development activities to validation of quantitative imaging tools and methods, it is important to evaluate the performance and clinical readiness of the tools before committing them to prospective clinical trials. A variety of tests, including special challenges and tool benchmarking, have been instituted within the network to prepare the quantitative imaging tools for service in clinical trials. This article highlights the benchmarking process and provides a current evaluation of several tools in their transition from development to validation.
美国国立癌症研究所的定量成像网络已运行10年，该网络内的研究团队正在开发和验证临床决策支持软件工具，以测量或预测癌症对各种疗法的反应。随着项目从开发活动推进到定量成像工具和方法的验证，在将这些工具投入前瞻性临床试验之前，评估其性能和临床适用性非常重要。该网络已开展了各种测试，包括特殊挑战和工具基准测试，以使定量成像工具为临床试验服务做好准备。本文重点介绍了基准测试过程，并对几种工具从开发到验证的过渡情况进行了当前评估。
