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[头颈部癌患者放射性龋齿的危险因素分析]

[Analysis of the risk factors of radiation-induced caries in patients with head and neck cancer].

作者信息

Wu Li-Ling, Gao Qing-Ping, Fu Qiong-Yao, Geng Kun

机构信息

Center of Stomatology, Xiangya Hospital, Central South University, Changsha 410008, China.

出版信息

Hua Xi Kou Qiang Yi Xue Za Zhi. 2019 Feb 1;37(1):87-91. doi: 10.7518/hxkq.2019.01.017.

Abstract

OBJECTIVE

This study aimed to evaluate the risk factors of radiation-induced caries by using a multiple linear regression equation and to provide the basis for the effective prevention of radioactive caries.

METHODS

A total of 166 patients with head and neck cancer who underwent radiotherapy were selected as subjects. The number of decayed, missing or filled surfaces were recorded. Questionnaire contents included age, sex, radiation dose, and radiotherapy techniques. Multiple stepwise regression analyses were performed to identify the risk factors of radiation-induced caries.

RESULTS

Multiple stepwise regression analyses indicated that the main risk factors of radiation-induced caries were plaque index, radiotherapy techniques, time after radiotherapy, and radiotherapy dose.

CONCLUSIONS

The awareness of dental care and caries treatment should be improved to reduce the occurrence of radiation-induced caries in patients with head and neck cancer. In addition, intensity modulated radiation therapy should be employed to decrease the radiation exposure dose received by teeth.

摘要

目的

本研究旨在运用多元线性回归方程评估放射性龋的危险因素,为有效预防放射性龋齿提供依据。

方法

选取166例接受放射治疗的头颈癌患者作为研究对象。记录龋失补牙面数。问卷内容包括年龄、性别、放射剂量和放疗技术。采用多元逐步回归分析确定放射性龋的危险因素。

结果

多元逐步回归分析表明,放射性龋的主要危险因素为菌斑指数、放疗技术、放疗后时间和放疗剂量。

结论

应提高对头颈部癌症患者口腔护理和龋齿治疗的认识,以减少放射性龋的发生。此外,应采用调强放射治疗以降低牙齿所接受的辐射暴露剂量。

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本文引用的文献

1
Cancer statistics in China, 2015.《中国癌症统计数据 2015》
CA Cancer J Clin. 2016 Mar-Apr;66(2):115-32. doi: 10.3322/caac.21338. Epub 2016 Jan 25.
2
Dental care during and after radiotherapy in head and neck cancer.头颈部癌症放疗期间及放疗后的口腔护理
Natl J Maxillofac Surg. 2014 Jul-Dec;5(2):117-25. doi: 10.4103/0975-5950.154812.
6
The effect of radiotherapy on dental hard tissue--a systematic review.放射治疗对牙齿硬组织的影响——一项系统综述。
Clin Oral Investig. 2014 Jan;18(1):17-24. doi: 10.1007/s00784-013-1034-z. Epub 2013 Jul 20.
8
The influence of parotid gland sparing on radiation damages of dental hard tissues.腮腺保留对牙体硬组织放射损伤的影响。
Clin Oral Investig. 2013 Jul;17(6):1619-25. doi: 10.1007/s00784-012-0854-6. Epub 2012 Oct 5.
10
Intensity-modulated radiotherapy in the treatment of head and neck cancer.调强放疗在头颈部癌症治疗中的应用。
Clin Oncol (R Coll Radiol). 2012 Sep;24(7):474-87. doi: 10.1016/j.clon.2012.05.006. Epub 2012 Jul 5.

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