Department of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Curr Opin Urol. 2019 May;29(3):210-215. doi: 10.1097/MOU.0000000000000601.
This review examines both trimodality therapy (TMT) in the definitive management of bladder cancer as well as the use of adjuvant radiotherapy for bladder cancer with a specific focus on publications from the last 2 years.
TMT is an effective management strategy for muscle invasive bladder cancer with outcomes similar to radical cystectomy. Effectiveness of this strategy exists in variant histologies and can be personalized with use of biomarkers. There is a role for adjuvant radiotherapy in locally advanced bladder cancer, especially in the age of improved imaging and modern radiotherapy techniques.
This review should provide the reader data necessary to support use of TMT and adjuvant radiation therapy in their clinic.
本文回顾了膀胱癌的根治性治疗中三联疗法（TMT）以及辅助放疗在膀胱癌中的应用，重点关注了过去 2 年的相关出版物。
TMT 是肌层浸润性膀胱癌的有效治疗策略，其结果与根治性膀胱切除术相似。该策略在不同的组织学类型中均有效，并且可以通过使用生物标志物进行个体化治疗。在局部晚期膀胱癌中，尤其是在影像学技术和现代放疗技术改进的时代，辅助放疗具有一定的作用。
本文应向读者提供支持在临床中使用 TMT 和辅助放疗的必要数据。
