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非医疗处方阿片类药物使用与自杀倾向之间关联的年龄差异。

Age differences in the association of nonmedical prescription opioid use and suicidality.

作者信息

Chan Keith T, Winston Priya, Jennings Rubin, Trant Jeffrey, Moller Mary

机构信息

Assistant Professor, School of Social Welfare, University at Albany, SUNY, Albany, New York.

Doctoral Student, School of Social Welfare, University at Albany, SUNY, Albany, New York.

出版信息

J Opioid Manag. 2019 Jan/Feb;15(1):5-10. doi: 10.5055/jom.2019.0480.

DOI:10.5055/jom.2019.0480
PMID:30855717
Abstract

OBJECTIVES

To examine age differences in the associations of nonmedical prescription opioid use (NMPOU) and suicidality.

DESIGN

This is a population health study using the 2016 National Survey on Drug Use and Health.

PARTICIPANTS

The sample included 38,136 persons 18 and older.

MAIN OUTCOME MEASURES

Weighted logistic regression analyses were used to examine the odds of past year NMPOU with suicidality (suicidal thoughts, plans, and attempts in the past year), stratified by age groups.

RESULTS

Overall, the prevalence of suicidality was higher for persons who reported past year NMPOU across all age groups. For the full sample, NMPOU was associated with increased odds of suicidal thoughts (OR = 1.71, 95% CI = 1.36, 2.14), plans (OR = 1.95, 95% CI = 1.33, 2.84), and attempts (OR = 2.25, 95% CI = 1.27, 4.00). Users 18 to 34 had greater odds for reporting yes on all three suicidality measures. Users 50 and older had greater odds for suicidal thoughts in the past year.

CONCLUSIONS

Among younger and older age groups, there is a higher prevalence and associated odds of suicidality for those who report any misuse within the 12-month period.

摘要

目的

研究非医疗处方阿片类药物使用(NMPOU)与自杀倾向之间关联的年龄差异。

设计

这是一项利用2016年全国药物使用和健康调查进行的人群健康研究。

参与者

样本包括38136名18岁及以上的人。

主要结局指标

采用加权逻辑回归分析,按年龄组分层,研究过去一年NMPOU与自杀倾向(过去一年的自杀念头、计划和企图)的几率。

结果

总体而言,在所有年龄组中,报告过去一年使用NMPOU的人的自杀倾向患病率更高。对于整个样本,NMPOU与自杀念头几率增加相关(比值比[OR]=1.71,95%置信区间[CI]=1.36,2.14)、计划(OR=1.95,95%CI=1.33,2.84)和企图(OR=2.25,95%CI=1.27,4.00)。18至34岁的使用者在所有三项自杀倾向指标上回答“是”的几率更高。50岁及以上的使用者过去一年有自杀念头的几率更高。

结论

在年轻和老年人群体中,在12个月内报告有任何滥用行为的人自杀倾向患病率和相关几率更高。

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