Mokaberinejad Roshanak, Rampisheh Zahra, Aliasl Jale, Akhtari Elham
a Department of Traditional Medicine , School of Traditional Medicine Shahid Beheshti University of Medical Sciences , Iran.
b Preventive Medicine and Public Health Research Center , Iran University of Medical Sciences , Tehran , Iran.
J Obstet Gynaecol. 2019 Jul;39(5):652-658. doi: 10.1080/01443615.2018.1541232. Epub 2019 Mar 11.
Oligomenorrhoea treatment with hormone therapy and Metformin is not usually well tolerated and is associated with a broad range of side effects. In Persian medicine, the management of oligomenorrhoea can be done with fennel and dry cupping. A clinical trial was conducted on 61 patients with oligomenorrhoea. The patients randomly received treatment for 6 months in two groups: fennel infusion plus dry cupping (Group A); versus treatment with Metformin (Group B). On the days between the two periods, the patients' BMI, pain levels and side effects were assessed. Thirty-one patients (mean age: 26.68) in Group A, and 30 patients (mean age: 28.90) in Group B were enrolled. The mean numbers of days between the two periods after 3 and 6 months in Group A was, respectively, 32.59 and 30.69, versus 40.66 and 431.22 in Group B. The mean pain severity dropped significantly in Group A. Fennel seed infusion plus a dry cupping uses a safe and effective therapeutic intervention in the management of oligomenorrhoea. IMPACT STATEMENT What is already known on this subject? Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women. Some common clinical manifestations of this syndrome include menstrual disorders such as oligomenorrhoea and amenorrhoea. The recommended therapeutic interventions include oral intervention, as well as metformin, which are associated with an increased risk of vascular thromboembolism, digestive complications such as nausea, and dizziness, and vitamin B12 deficiency. Therefore, the use of complementary medicine in controlling and treating PCOS is considered a valuable intervention in conventional medicine. In Persian traditional medicine, medicinal fennel (with the scientific name of Foeniculum Vulgare Mill) is commonly used in this regard. The practice of dry cupping during the monthly period that ends with ovulation is also recommended. What do the results of this study add? The present study concludes that fennel seed infusion plus a dry cupping therapy is effective and safe in reducing the days between two menstrual periods and manages oligomenorrhoea. What are the implications of these findings for clinical practice and/or further research? A clinical study is suggested for assessing the effect of fennel seed infusion plus dry cupping on oligomenorrhoea, with a large sample size and a longer follow up time.
激素疗法和二甲双胍治疗月经过少通常耐受性不佳，且伴有一系列副作用。在波斯医学中，小茴香和拔火罐可用于治疗月经过少。对61例月经过少患者进行了一项临床试验。患者随机分为两组，接受为期6个月的治疗：小茴香冲剂加拔火罐（A组）；与二甲双胍治疗（B组）。在两个疗程之间的日子里，评估患者的体重指数、疼痛程度和副作用。A组纳入31例患者（平均年龄：26.68岁），B组纳入30例患者（平均年龄：28.90岁）。A组在3个月和6个月后两个疗程之间的平均天数分别为32.59天和30.69天，而B组为40.66天和431.22天。A组的平均疼痛严重程度显著下降。小茴香籽冲剂加拔火罐是治疗月经过少的一种安全有效的治疗干预措施。影响声明关于这个主题已知的信息是什么？多囊卵巢综合征（PCOS）是女性常见的内分泌疾病。该综合征的一些常见临床表现包括月经紊乱，如月经过少和闭经。推荐的治疗干预措施包括口服药物以及二甲双胍，但这些治疗与血管血栓栓塞风险增加、恶心和头晕等消化系统并发症以及维生素B12缺乏有关。因此，在控制和治疗PCOS方面使用补充医学被认为是传统医学中有价值的干预措施。在波斯传统医学中，药用小茴香（学名Foeniculum Vulgare Mill）常用于此。也建议在以排卵结束的月经期进行拔火罐治疗。这项研究的结果增加了什么？本研究得出结论，小茴香籽冲剂加拔火罐疗法在减少两个月经周期之间的天数和治疗月经过少方面是有效且安全的。这些发现对临床实践和/或进一步研究有什么影响？建议进行一项临床研究，以评估小茴香籽冲剂加拔火罐对月经过少的影响，样本量要大且随访时间要长。
